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Barriers and Enablers of Antiplatelet Adherence After PCI

November 15, 2025
in Medicine
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In a groundbreaking study conducted across several healthcare institutions in Saudi Arabia, researchers have delved into the intricate world of antiplatelet therapy adherence following percutaneous coronary interventions (PCI). Antiplatelet medications are crucial for patients recovering from heart conditions, particularly those who have undergone PCI, a common procedure used to treat coronary artery disease. The study highlights the multifaceted barriers and enablers influencing healthcare professionals’ perspectives on patient adherence to these life-saving medications, ultimately shedding light on a critical aspect of post-operative care.

The research stems from an urgent need to ensure that patients who have undergone PCI continue to take their prescribed antiplatelet therapy as directed. Non-adherence to such recommendations can lead to dire consequences, including the recurrence of cardiovascular events. The study aims to explore the perceptions of healthcare providers who are on the front lines of patient care, including doctors, nurses, and pharmacists, thus providing a comprehensive overview of their experiences and challenges regarding medication adherence.

One notable finding from the study is the significant presence of communication barriers in the healthcare setting. Professionals indicated that misunderstandings between medical staff and patients often contributed to patients not fully grasping the importance of their antiplatelet regimens. Many patients appeared to have varying levels of health literacy, which complicated discussions around medication adherence. This gap in understanding can result in patients failing to appreciate the significance of their therapy in preventing future cardiovascular complications.

Interestingly, the study also emphasizes the enablers that can enhance patient adherence to antiplatelet therapy. Healthcare professionals identified the pivotal role of thorough patient education highlighting the need for clear communication regarding the purpose and benefits of antiplatelet medications. When patients are effectively informed about how these medications work to prevent blood clots and protect their heart health, they are more likely to commit to their prescribed regimens.

Moreover, the role of follow-up care emerged as a crucial aspect influencing adherence. The study revealed that regular follow-ups and check-ins with patients foster a sense of accountability and support, making them more likely to adhere to their medication schedules. Building a rapport through frequent interactions allows healthcare professionals to address any concerns, answer questions, and provide reassurances, all of which contribute to a positive adherence experience.

The influence of cultural factors on medication adherence was another compelling aspect uncovered during the research. The healthcare professionals recognized that cultural beliefs and societal norms had a profound impact on patient attitudes towards medications. In some cases, traditional medicine practices might discourage patients from adhering to prescribed treatments, leading to conflicting viewpoints on the necessity of antiplatelet therapy and contributing to non-compliance.

The findings reveal that the healthcare environment itself can either hinder or promote patient adherence. Workload pressures, staff shortages, and high patient-to-nurse ratios can impede the ability of healthcare professionals to provide individualized attention to patients. Consequently, when healthcare providers are overwhelmed, they may have less time to engage meaningfully with patients, potentially affecting the quality of education around medication adherence and ultimately impacting patient outcomes.

Interestingly, the study also pointed to the potential of technology as a tool for improving adherence rates. Many healthcare providers expressed enthusiasm for utilizing mobile applications and reminder systems to prompt patients to take their medications. The study’s respondents believed that technological solutions could bridge the communication gap and reinforce the importance of adherence outside clinical settings, thereby making it easier for patients to remain on track with their prescribed therapies.

Certainly, the input from healthcare professionals regarding systemic challenges also highlighted the limitations of current healthcare policies surrounding post-PCI care. Inadequate reimbursement models for follow-up consultations and patient education efforts were cited as hurdles. Many healthcare professionals felt that policy changes prioritizing adherence education and follow-up care could vastly improve patient outcomes and potentially reduce the healthcare burden associated with recurrent cardiovascular events.

In summation, the study underscores not just the barriers that impede antiplatelet adherence, but also shines a light on actionable solutions that stem from healthcare professionals’ insights. Understanding these challenges and embracing effective strategies can pave the way for enhanced adherence rates, ultimately leading to better outcomes for patients following PCI. As the healthcare landscape continues to evolve, integrating the perspectives of those directly involved in patient care remains crucial for driving improvements in adherence and chronic disease management.

The implications of this research extend beyond the specific confines of Saudi Arabia, shedding light on a universal challenge faced by healthcare systems worldwide. By embracing collaborative efforts to address barriers and enhance support mechanisms, healthcare providers across the globe can work towards ensuring that patients are not only informed but empowered to maintain their antiplatelet therapies following PCI, thus fulfilling the goal of optimal cardiovascular health.

With such revelations emerging from this dedicated qualitative study, the hopes for improving patient care practices stand strong. The recommendations drawn from healthcare professionals’ perspectives can be instrumental in shaping policies and reforming existing practices to foster a culture of adherence — a paradigm shift that could ultimately lead to lives saved and improved quality of life for countless patients navigating their recovery journey.

As efforts continue to translate research into practice, it is imperative that we listen to the voices of healthcare professionals who understand the nuances of their patients’ challenges. By fostering open dialogue, utilizing technology, and enhancing education, the gap between prescription and adherence can be effectively bridged, ensuring that patients reap the full benefits of their antiplatelet therapies.

Through this study, we are reminded of the vital role that continuous education, patient-centered communication, and systemic support play in the journey towards optimal patient adherence. Let us remain vigilant in fostering an environment where healthcare professionals feel empowered to advocate for their patients’ adherence, leading us towards a future where the negative impacts of non-adherence become a relic of the past.

The findings of this research hold the promise of establishing best practices and paving the way for enhanced patient care protocols that prioritize adherence to antiplatelet therapy post-PCI. In doing so, we nurture a healthier society, ensuring that individuals are not lost to unnecessary complications, but rather supported through their recovery towards holistic health and wellness.

In conclusion, the exploration of healthcare professionals’ perspectives on barriers and enablers of antiplatelet adherence opens new avenues for study and improvement. It emphasizes a collaborative approach, prioritizing education, and understanding patient needs as crucial steps in the journey of recovery post-PCI.


Subject of Research: Barriers and enablers of antiplatelet adherence after PCI

Article Title: Exploring healthcare professionals’ perspectives on barriers and enablers of antiplatelet adherence after PCI: a multisite qualitative study in Saudi Arabia

Article References:

Alodhailah, A.M., Lam, L., Almutairi, A.A. et al. Exploring healthcare professionals’ perspectives on barriers and enablers of antiplatelet adherence after PCI: a multisite qualitative study in Saudi Arabia. BMC Nurs 24, 1393 (2025). https://doi.org/10.1186/s12912-025-04067-9

Image Credits: AI Generated

DOI: https://doi.org/10.1186/s12912-025-04067-9

Keywords: Antiplatelet therapy, PCI, healthcare professionals, medication adherence, patient education, follow-up care, cultural factors, technology in healthcare, systemic challenges.

Tags: antiplatelet medication importanceantiplatelet therapy adherencebarriers to medication adherencecardiovascular event recurrence preventioncommunication issues in healthcareenablers of patient adherencehealthcare provider perspectivesinterdisciplinary healthcare teamworkpatient education in cardiologypercutaneous coronary intervention outcomespost-operative care challengesSaudi Arabia healthcare study
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