Lysosomal pH emerges as a context-dependent amplifier in septic lung injury
A review identifies lysosomal pH dysregulation as a plausible context-dependent amplifier of sepsis-associated lung injury, but finds that most supporting ...
Tag: v-ATPase
Somatic Cells Kill Germline Cysts by Acidification, Review Finds
A new review synthesises evidence that somatic support cells eliminate germline cysts in flies and mice through a conserved non-apoptotic ...
Lens Capsule Proteomics Reveals Lysosomal Breakdown Linking Cataract and Glaucoma
Proteomic analysis of human anterior lens capsules reveals that ATP6V1A-associated lysosomal dysfunction links elevated eye pressure and lens epithelial injury ...
Scientists Find Druggable Switch That Controls the Cell’s Master Recycling Regulator TFEB
A Nature study from TIGEM reveals a previously unknown TBK1-ULK1 signaling pathway that controls the master recycling regulator TFEB, exposing ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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