Hidden Protein Signals Decide Why Immunotherapy Fails in Gut Cancers
A new review maps how secreted protein circuits in gastrointestinal tumours govern immune recruitment, suppression and response to checkpoint immunotherapy.
Tag: tumour microenvironment
Nanomedicines Offer New Routes Past the Brain’s Defenses Against Drug-Resistant Tumours
A new review in Molecular Cancer details how five classes of nanomaterials could breach the blood–brain barrier and dismantle the ...
Lab-Grown Tumours and Digital Twins Bring Precision Therapy to Oesophageal Cancer
A new review maps the laboratory models—from organoids to humanised mice to computational pipelines—that could finally bring personalised treatment to ...
Dark DNA’s Long RNAs Emerge as Master Regulators of Colorectal Cancer
A major new review shows that long non-coding RNAs orchestrate the colorectal cancer tumour microenvironment, offering new biomarkers and therapeutic ...
PET Imaging Reveals Whether Immunotherapy Drugs Actually Reach Their Tumour Targets
Researchers are using PD-L1-targeted PET/CT imaging to directly visualise whether the immunotherapy drug atezolizumab saturates its target in tumours, offering ...
Hidden messengers: matrix-bound vesicles rewrite the rules of tissue signalling
A new review argues that matrix-bound extracellular vesicles retained within the extracellular matrix form a distinct, tissue-specific signalling population with ...
Smart Nanoparticles Reprogram Tumour Defenses to Boost Immune Attack on Cancer
Adelaide University researchers have developed mRNA lipid nanoparticles that reprogram immunosuppressive tumour-associated macrophages to recruit cancer-fighting T cells, showing reduced ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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