One Gene, Two Proteins: Why CFH Cancer Biomarker Studies May Be Measuring the Wrong Molecule
A new commentary in BMC Cancer warns that pan-cancer studies treating CFH as a single cancer biomarker have been measuring ...
Tag: tumour microenvironment
How a Cellular Stress Switch Helps Tumours Hide From the Immune System
A new review reveals how the unfolded protein response, a cellular stress-signalling network, helps tumours evade immune detection and could ...
AI Reads Tissue Maps to Forecast Cancer Survival, Cell by Cell
An explainable graph neural network called SpaCEy identifies the spatial tissue patterns and protein markers that predict cancer survival and ...
Beyond target expression: a modular framework to predict who benefits from antibody–drug conjugates
A Nature Reviews Clinical Oncology Review proposes a modular biomarker framework that moves ADC patient selection beyond semi-quantitative immunohistochemistry by ...
The Hidden Switch That Helps Breast Cancer Survive and Resist Treatment
A comprehensive new review maps how NF-κB signalling drives breast cancer progression, subtype-specific therapy resistance and tumour-microenvironment crosstalk, and argues ...
Immune Receptor LAIR1 Blocks Cancer Cell Engulfment in Brain Tumours
New research in the British Journal of Cancer shows that the collagen-binding receptor LAIR1 disables the phagocytic machinery of glioma-associated ...
Metabolism Holds the Key to Stronger CAR T Cell Therapies, Review Argues
A Nature Reviews Cancer review argues that metabolism, from CAR design and manufacturing conditions to the patient's diet, is a ...
Exercise Emerges as a Serious Candidate Therapy in Cancer Prevention and Treatment
A new Nature Reviews Clinical Oncology review synthesizes epidemiological, trial and mechanistic evidence to argue that structured exercise is emerging ...
How Lung Cancer Rewires Fat Metabolism to Grow, Spread, and Evade Treatment
A new review in the Journal of Translational Medicine maps how non-small cell lung cancer rewires lipid metabolism to fuel ...
Nanovaccine Built From Metal–Organic Frameworks Drives Tumours Into Full Retreat
A metal–organic framework nanovaccine co-delivering tumour antigens and STING agonists induced systemic tumour regression, immune memory and synergy with radiotherapy ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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