Long non-coding RNA TMPO-AS1 flags poor outcomes in lung adenocarcinoma
A multi-database bioinformatics study identifies the long non-coding RNA TMPO-AS1 as overexpressed in lung adenocarcinoma and linked to poor survival ...
Tag: tumor immune microenvironment
Biomarkers point to which lymphoma patients respond to dasatinib
A Phase II trial in Japan identified TCR signaling mutations and clonal hematopoiesis burden as biomarkers predicting dasatinib response in ...
RNA Methylation Enzyme NSUN2 Keeps Lung Tumors Cold and Blocks Immunotherapy
A new study reports that the RNA m5C methyltransferase NSUN2 suppresses CCL5-driven CD8+ T cell recruitment in lung adenocarcinoma through ...
Immune Cell Genes Track Ferroptosis Signals in Kidney Cancer
A multi-cohort study finds that five genes upregulated in clear cell renal cell carcinoma mark the immune microenvironment rather than ...
AI pathology model stratifies glioma patient risk across 2,552 cases
A multicenter study reports a Vision Transformer-based pathology framework whose risk scores, validated in 2,552 glioma cases, predict survival and ...
Resistant Melanoma Cells Recruit Immune Cells to Thwart Targeted Therapy
BRAF inhibitor-resistant melanoma cells release M-CSF and remodel the immune microenvironment, and blocking this signal improved drug efficacy in mouse ...
S100P Emerges as a Prognostic and Immune-Linked Biomarker in Lung Adenocarcinoma
A bioinformatics and single-cell study finds that S100P is elevated in lung adenocarcinoma, tracks with advanced stage and poorer survival, ...
CT83 Protein Marks Triple-Negative Breast Cancer, but Its Aggressive Links Prove Indirect
A study of 222 breast cancer patients found CT83 expression in nearly half of tumors, with its ties to aggressive ...
Gene Signature Tied to Folate Metabolism Predicts Liver Cancer Survival Unevenly
A 20-gene folate metabolism signature predicted hepatocellular carcinoma survival in some cohorts but failed in another, and the glutathione synthetase ...
Endothelial ICAM-1 Polarization Traps T Cells at Melanoma Tumor Edges
Endothelial ICAM-1 becomes polarized to the tumor periphery as melanomas grow, trapping T cells at the margins, and blocking it ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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