S100P Emerges as a Prognostic and Immune-Linked Biomarker in Lung Adenocarcinoma
A bioinformatics and single-cell study finds that S100P is elevated in lung adenocarcinoma, tracks with advanced stage and poorer survival, ...
Tag: tumor immune microenvironment
CT83 Protein Marks Triple-Negative Breast Cancer, but Its Aggressive Links Prove Indirect
A study of 222 breast cancer patients found CT83 expression in nearly half of tumors, with its ties to aggressive ...
Gene Signature Tied to Folate Metabolism Predicts Liver Cancer Survival Unevenly
A 20-gene folate metabolism signature predicted hepatocellular carcinoma survival in some cohorts but failed in another, and the glutathione synthetase ...
Endothelial ICAM-1 Polarization Traps T Cells at Melanoma Tumor Edges
Endothelial ICAM-1 becomes polarized to the tumor periphery as melanomas grow, trapping T cells at the margins, and blocking it ...
Bladder cancer immune landscape is compartmentalized, treatment-modified, and context dependent
A new narrative review finds that the clinical meaning of immune infiltration in bladder cancer depends on cell localization, functional ...
Lactylation gene signature predicts outcomes in clear cell renal cell carcinoma
A machine-learning 15-gene lactylation signature predicts prognosis and drug response in clear cell renal cell carcinoma, with CCNA2 identified as ...
Therapy-induced senescence reshapes the tumor immune microenvironment, review argues
A review in Molecular Biology Reports examines how therapy-induced senescence and the SASP reshape the tumor immune microenvironment, and how ...
Eight-Gene Signature Ties Immune Landscape to Gastric Cancer Survival
An integrated transcriptomic and tissue-level study links an eight-gene risk score and the immune regulator RGS1 to survival in gastric ...
B7-H3 blockade and MEK inhibition overcome immune defenses in prostate cancer models
In preclinical castration-resistant prostate cancer models, combining B7-H3 blockade with the MEK inhibitor trametinib overcame compensatory immune suppression and structural ...
OSBPL3 Shapes Colorectal Cancer Progression Through Gut Microbes and Immune Microenvironment
New research links the lipid-binding protein OSBPL3 to colorectal cancer progression, gut microbiota shifts, and immune microenvironment changes, with two ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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