Parasites Build Layered Defenses to Outsmart Malaria and Kinetoplastid Drugs
A systematic review of Plasmodium, Leishmania, and Trypanosoma reveals that drug resistance emerges through interconnected mechanisms of altered transport, target ...
Tag: Trypanosoma brucei
Sleeping Sickness Parasite Invades the Uterus and Disrupts Reproductive Hormones
A new study in PLOS Pathogens shows that Trypanosoma brucei invades the uterine lining, remodels the reproductive immune environment, and ...
Two Trypanosome Species, Same Parasite Burden, Very Different Fates in Mice
A controlled mouse study shows that Trypanosoma congolense and Trypanosoma brucei produce similar parasite burdens and organ damage but sharply ...
Fever Turns the Tables on Sleeping Sickness Parasites, Study Finds
New research shows that host fever, through mitochondrial damage, oxidative stress and metabolic disruption, rapidly destroys the transmission-ready stumpy form ...
Trypanosome ESCRT Study Reveals Novel Components and Ancient Eukaryotic Machinery
A new BMC Biology study shows that trypanosomes use a heteropentameric ESCRT-I complex and an ancient Tom1-based sorting pathway, reshaping ...
Scientists Design a Computationally Engineered mRNA Vaccine Candidate Against Sleeping Sickness Parasite
Researchers have used immunoinformatics and reverse vaccinology to design a multi-epitope mRNA vaccine candidate against Trypanosoma brucei, the parasite that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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