Novel kynureninase inhibitor KS79356 slows triple-negative breast cancer progression
Researchers at King Khalid University have identified a small molecule, KS79356, that potently blocks the growth, invasion, and migration of ...
Tag: triple-negative breast cancer
Targeting MINK1 disrupts glucose metabolism to suppress triple-negative breast cancer
Triple-negative breast cancer, the most aggressive and hardest-to-treat form of breast cancer, may have a newly exposed weak point. A ...
Early Treatment Attrition After Recurrence Following Neoadjuvant Chemo-Immunotherapy in Triple-Negative Breast Cancer
Triple-negative breast cancer is sending researchers back to a difficult question: what happens when an aggressive tumor returns after receiving ...
Scientists discover molecule fueling one of breast cancer’s deadliest forms
Australian researchers have identified a molecular vulnerability that could help explain why triple-negative breast cancer so readily spreads through the ...
New master switch linked to aggressive breast cancer; drug slows tumour growth
Researchers at the Yong Loo Lin School of Medicine at the National University of Singapore have identified a molecular “master ...
Preoperative Dual Immunotherapy Shows Promise in High-Risk Early HER2-Negative Breast Cancer
WASHINGTON — A combination of two immunotherapy drugs produced substantially higher rates of tumor eradication when added to chemotherapy before ...
Atezolizumab After Single or Multiple Fractions of Stereotactic Radiotherapy in TNBC
Advanced triple-negative breast cancer may benefit from an unexpected combination: stereotactic ablative body radiotherapy (SABR) delivered either in a single ...
LIG1 Loss Reveals Targetable Weakness Against Chemotherapy-Resistant Triple-Negative Breast Cancer
In triple-negative breast cancer (TNBC) that carries TP53 mutations, loss of one copy of the DNA ligase I gene (LIG1) ...
Single-Cell Multi-Omics Reveals Cancer-Associated Fibroblast Programs in Breast Cancer
A groundbreaking study has unveiled new insights into the complex biology of cancer-associated fibroblasts (CAFs) within triple-negative breast cancer (TNBC), ...
Olaparib Benefits HR-Deficient TNBC and Platinum-Sensitive Ovarian Cancers
In a groundbreaking phase 2 clinical trial, researchers have demonstrated the efficacy of olaparib, a PARP inhibitor, in treating metastatic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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