Blocking a Nerve-Linked Ion Channel Turns Tumor Cell Stress Into Fatal Ferroptosis
A preclinical nanoplatform that blocks the TRPA1 ion channel while delivering glucose starvation, chemodynamic, and sonodynamic therapy suppressed tumor growth ...
Tag: triple-negative breast cancer
AI pathology scoring flags longer survival on pembrolizumab in metastatic triple-negative breast cancer
An AI-based digital pathology assessment of PD-L1 identified metastatic triple-negative breast cancer patients with longer progression-free survival on pembrolizumab in ...
GPR54 activates YAP via Gαq/11–RhoA axis in triple-negative breast cancer
A new study shows that the kisspeptin receptor GPR54 activates the YAP oncoprotein through a Gαq/11–RhoA signaling cascade, driving tumor ...
Rare breast cancer case survives 21 months after leptomeningeal spread
A Taiwanese case report documents 21-month survival after leptomeningeal metastasis in a rare triple-negative breast cancer subtype treated with sacituzumab ...
Engineered vesicles deliver miR-204 to triple-negative breast cancer cells in preclinical tests
Researchers engineered GE11-targeted vesicles that delivered tumor-suppressive miR-204 into EGFR1-positive triple-negative breast cancer cells, inhibiting their growth in lab and ...
Neutrophils Shift Metabolism in a Triple-Negative Breast Cancer Coculture Model
A lab coculture study found that adding neutrophils increased mitochondrial activity in a triple-negative breast cancer and fibroblast model.
Plant-Derived Nanoparticles Restore Tumor-Suppressor miR-34a to Block NOTCH1 in Triple-Negative Breast Cancer
Folate-functionalized chitosan nanoparticles carrying an Ailanthus excelsa stembark extract restored miR-34a and suppressed NOTCH1 signaling, reducing tumor growth, metastasis and ...
CT83 Protein Marks Triple-Negative Breast Cancer, but Its Aggressive Links Prove Indirect
A study of 222 breast cancer patients found CT83 expression in nearly half of tumors, with its ties to aggressive ...
Treatment delays raise death risk in stage III breast cancer, Korean cohort finds
A nationwide Korean cohort study of 16,495 women found that treatment delays of 61 days or more were associated with ...
Metabolism, immunity and the microbiome shape the breast cancer microenvironment
A new Frontiers in Oncology Research Topic gathers six articles examining how metabolism, inflammation, immunity and the gut microbiome influence ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!