Genetic and cell studies point to miR-539-3p–SOX9 pattern in keloids
A multi-method study prioritized miR-539-3p and SOX9 as linked candidates in keloid tissue and fibroblasts, while leaving their regulatory relationship ...
Tag: Transcriptomics
Candidate grapevine rust effectors suppress AvrB-triggered plant cell death in laboratory assay
A transcriptomic, microscopy and functional study of Neophysopella tropicalis identified 303 candidate effectors, including six that suppressed AvrB-triggered plant cell ...
Synthetic organelle records transient gene activity in human cells
A mitochondria-anchored synthetic organelle captured up to 90% of expressed gene transcripts in human cells and preserved transient interferon-response histories ...
TIMP1 linked to anoikis resistance and metastasis in esophageal cancer
Single-cell and bulk transcriptomic analyses linked TIMP1 to anoikis resistance in esophageal squamous cell carcinoma, while cell and mouse experiments ...
Gut microbes track pigeon muscle quality differences in multi-omics study
A multi-omics comparison links strain-specific gut microbes and intestinal features to candidate differences in pigeon breast-muscle metabolism and meat quality, ...
Blood RNA markers illuminate protein-modification networks in heart attacks
A transcriptomic study identified GABARAPL1, PELI1 and NLRP3 as elevated blood RNA markers associated with acute myocardial infarction, while highlighting ...
Quercetin reduces acute inflammatory and matrix-remodeling markers in mouse intracerebral hemorrhage
An experimental study found that quercetin reduced selected inflammatory and extracellular matrix-remodeling markers 24 hours after mouse intracerebral hemorrhage, while ...
MSIPep prioritizes tumor peptides in leukemia and solid-tumor datasets
MSIPep combines immunopeptidomics, transcriptomics and deep learning to identify and computationally prioritize candidate tumor peptides in leukemia and solid-tumor datasets.
Gene architecture predicts isoform diversity across four genomes
Longer introns, shorter exons and more complex gene organization were consistently associated with higher transcript-isoform diversity in humans, mice, flies ...
Network and cell study links carboplatin to four melanoma targets
Network analysis and B16F0 cell experiments linked carboplatin with CDKN1A, BRCA1, PTEN and AKT1 in melanoma, without establishing clinical benefit.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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