Tag: TGF-beta signaling

New research identifies the secreted protein SRPX2 as a molecular switch that stabilizes the TGF-beta receptor to drive metastasis and ...

By merging bulk and single-cell RNA sequencing with machine learning and lab experiments, researchers have identified smooth muscle cells as ...

A new transcriptomic study maps eight embryonic stages of the giant river prawn, revealing a massive early genetic shift consistent ...

A new study links SGLT2 inhibitor therapy with reduced circulating activin A, improved right-heart function, and modulation of BMP/activin signaling ...

Researchers at Harbin Medical University report that the RNA-binding protein PTBP3 stabilizes SMAD3 mRNA and drives podocyte epithelial-to-mesenchymal transition, and ...

Single-cell transcriptomics across multiple COVID-19 cohorts reveals that peripheral B cell dysregulation, marked by plasmablast expansion and naive B cell ...

Researchers report that M2 macrophage-derived exosomal miR-350-5p accelerates pulmonary fibrosis by suppressing Smad7 and amplifying TGF-beta signaling in lung fibroblasts ...

Researchers engineered anti-FAP-targeted exosomes loaded with pirfenidone and showed that nebulized delivery outperforms intravenous injection in treating pulmonary fibrosis in ...

Transcriptome sequencing of brain, liver and muscle tissue has revealed that TGF-beta signaling and related pathways are activated in fast-growing ...

A new review details how extracellular vesicles and their microRNA cargo drive pulmonary fibrosis while also offering promising diagnostic biomarkers ...