Eight-Gene Signature Ties Immune Landscape to Gastric Cancer Survival
An integrated transcriptomic and tissue-level study links an eight-gene risk score and the immune regulator RGS1 to survival in gastric ...
Tag: TCGA
lncRNA decay hypothesis cannot be tested with current half-life coverage
A new analysis finds that only a small fraction of annotated long non-coding RNAs have measured half-lives, leaving the proposed ...
TCGA study links coagulation-associated lncRNAs to prostate cancer prognosis
A TCGA-based prostate cancer study developed a coagulation-associated lncRNA prognostic signature, found distinct immune-related features in high-risk patients, and showed ...
Checkpoint Gene Signatures Reveal Three Melanoma Immune Types With Sharply Different Survival Odds
A multi-cohort re-analysis of melanoma transcriptomes and single-cell immune data links coordinated checkpoint-gene expression to longer overall survival, treatment-related immune ...
AI Reads Tumor Slides and Genes Together to Flag Hidden Risk in Early-Stage Endometrial Cancer
A new interpretable AI model called PRISM combines pathology slides with transcriptomic pathway data to sharpen progression-risk prediction in early-stage ...
When TERT Mutates Alone: A Hidden High-Risk Group in Papillary Thyroid Cancer
An exploratory analysis of TCGA data suggests that isolated TERT promoter mutation, without BRAF V600E, may mark the worst-prognosis subgroup ...
Tiny miR-15a-5p emerges as central switch in ovarian cancer angiogenesis network
An integrated miRNA–mRNA network study in ovarian cancer places miR-15a-5p at the center of an angiogenic module and highlights epithelial ...
Silenced Thyroid Gene CRABP1 Signals Aggressive Cancer Cells, Study Finds
A single-cell and epigenetic study links loss of the retinoid-binding protein CRABP1 to an invasive malignant epithelial cell state in ...
Sulphur-handling genes track colorectal cancer molecular subtypes across seven cohorts
A multicohort transcriptomic analysis shows that a predefined 14-gene sulphur-handling programme is reproducibly linked to colorectal cancer consensus molecular subtypes, ...
Climbing the causal ladder: a new framework sorts real cancer drug targets from statistical noise
A new evidence-accounting framework called the Causal Integration Ladder separates statistical association from causal, therapeutically tractable mechanism in cervical cancer, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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