Zinc Complexes Emerge as Safer Rivals to Platinum Cancer Drugs, Landmark Review Finds
A systematic review of 66 zinc(II) Schiff base complexes shows that octahedral geometry and red-shifted imine infrared signatures predict potent, ...
Tag: Structure-activity relationships
Pyrazole Chemistry Surges as New Wave of Bioactive Derivatives Emerges in 2025 and 2026
A new review consolidates the 2025-2026 wave of pyrazole derivatives, revealing sub-micromolar anticancer leads, nanogel delivery gains, nanomolar enzyme inhibitors ...
Plant-Derived Sesquiterpenoids Show Potent Dual Attack on Lung Cancer Cells
Chemists isolated 28 sesquiterpenoids from the medicinal herb Carpesium abrotanoides, including five new compounds, and found that one of them ...
Plant-Inspired Synthetic Molecules Show Fresh Promise Against Alzheimer’s Enzyme
A new review shows that synthetic derivatives of plant-based scaffolds such as coumarin, xanthone, chalcone, quinoline, and quinazoline can inhibit ...
How Sugar Bonds Shape Flavonoid Power in Food and Health
A new review explains how the carbon–carbon sugar bond of flavonoid C-glycosides shapes their stability, metabolism, and potential in functional ...
How Extraction Methods Program the Healing Power of Mushroom Polysaccharides
A new review introduces an Extraction–Structure–Activity Relationship framework showing that how mushroom polysaccharides are extracted determines their molecular structure and ...
Dual PROTACs Close In on Two Disease Proteins at Once
A new review in Molecular Diversity charts the rapid rise of dual PROTACs, single molecules engineered to destroy two disease-driving ...
Creating N-Heterocyclic Protease Inhibitors for Flaviviruses
In recent years, the fight against flaviviral infections has taken on a new level of urgency within the scientific community. ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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