Tag: Structure-activity relationships

A comprehensive ten-year medicinal chemistry review analyzes how structural modifications, trapping potency, and multi-target hybrids shape the clinical efficacy and ...

A comprehensive scientific review details how natural polysaccharide nanocarriers remodel the immunosuppressive liver tumor microenvironment by repolarizing macrophages, activating innate ...

A new review argues that pyrazolopyridine derivatives show therapeutic potential against Alzheimer's disease and distils the structural rules for designing ...

A marine sponge-derived fungus from Vietnam yielded twelve secondary metabolites, including one reported for the first time from the species, ...

A comprehensive review of soybean paste functional peptides covering fermentation-driven formation, characterization, classification, structure-activity relationships, and multi-omics insights.

Medicinal chemists... The histamine receptor family offers a striking example of how a single small molecule can orchestrate profoundly different ...

Chemists have converted the anti-inflammatory drug diflunisal into fluorinated biphenyl ureas that kill Mycobacterium kansasii at nanomolar-scale concentrations while leaving ...

A systematic review of 66 zinc(II) Schiff base complexes shows that octahedral geometry and red-shifted imine infrared signatures predict potent, ...

A new review consolidates the 2025-2026 wave of pyrazole derivatives, revealing sub-micromolar anticancer leads, nanogel delivery gains, nanomolar enzyme inhibitors ...

Chemists isolated 28 sesquiterpenoids from the medicinal herb Carpesium abrotanoides, including five new compounds, and found that one of them ...