Scientists Capture the Spliceosome in the Act of Shutting Itself Down
Cryo-electron microscopy structures of human spliceosomes reveal the sequential roles of the helicases Aquarius, DHX15 and DHX35, together with newly ...
Tag: spliceosome
Hidden RNA switches reshape cancer proteins and sabotage drug targets
A comprehensive multi-omics study catalogues thousands of cancer-specific isoform switches in melanoma, ovarian cancer, and AML, showing that most disrupt ...
Hidden RNA Codes: How Splicing and Non-Coding RNAs Help Plants Survive Stress
A new review synthesizes evidence that alternative splicing and long non-coding RNAs form an integrated RNA regulatory network that underpins ...
Stress-Triggered SMN Droplets Act as a Rescue System for Misplaced Splicing Machinery
Researchers in Bonn have discovered that the SMN protein forms reversible cytoplasmic condensates under stress to trap and clear misplaced ...
Splicing Factor SRSF7 Emerges as a Master Switch Behind Triple-Negative Breast Cancer Spread
Researchers in the Netherlands identified the RNA splicing factor SRSF7 as a key regulator of migration, invasion, and lung metastasis ...
SON Protein Keeps GC-Rich Genes Splicing Smoothly, Study Reveals
A new Cell Research study shows that the nuclear speckle scaffold protein SON enables efficient splicing of GC-rich genes by ...
RNA Genes Emerge as Hidden Culprits in Inherited Blindness
Variants in the small nuclear RNA genes RNU4-2 and RNU6 paralogs account for two percent of autosomal dominant retinitis pigmentosa ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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