Inflammation-Driven Spatial Niche Sets the Stage for Early Gastric Cancer
A spatial multi-omics study in Chinese Medical Journal shows that early gastric cancer arises within an inflammation-associated spatial niche governed ...
Tag: Spatial transcriptomics
Three Cell Subclusters Uncovered as Drivers of Pancreatic Cancer Cachexia
University of Oklahoma researchers have identified three adjacent cell subclusters in pancreatic tumors that form a feed-forward network driving cancer ...
New Spatial Transcriptomics Tool Maps Gene Expression Across Tissue Boundaries in the Developing Mouse Brain
Researchers have developed REBOSEP, a computational workflow that maps gene expression as a continuous signal across tissue boundaries and reveals ...
CellART turns blurry spatial gene maps into crisp single-cell atlases
A new computational framework called CellART unifies cell segmentation and cell-type annotation across high-resolution spatial transcriptomics platforms, revealing single-cell detail ...
c-MET Signaling Reshapes the Lung Cancer Immune Landscape in Space and Metabolism
A new review in the Journal of Translational Medicine argues that c-MET signaling shapes spatially confined, metabolically driven immunosuppressive niches ...
Gene Atlas Reveals How Norway Spruce Finally Learns to Flower
Swedish researchers have built a spatial gene atlas of Norway spruce cone development, identifying key reproductive genes and a previously ...
Immunotherapy Breakthroughs and Single-Cell Atlas Studies Reshape Liver Cancer Care in China
A 2023 review from Fudan University documents how Chinese clinical trials and single-cell omics studies are transforming the treatment and ...
MRI Scans Reveal Hidden Cell Neighborhoods That May Signal Breast Cancer Spread
Researchers at Fudan University Shanghai Cancer Center have linked MRI-visible features such as background parenchymal enhancement and peritumoral edema to ...
Inside Tumors’ Hidden Immune Hubs: Spatial Maps Reveal Zoned Architecture of Tertiary Lymphoid Structures
A new spatial transcriptomics study shows that tertiary lymphoid structures in tumors are spatially zoned immune organs whose core-periphery organization ...
Liver Cancer Gene GNG4 Found to Build Walls That Keep Immune Cells Out of Tumors
New research links the gene GNG4 in malignant liver cells to tumor immune exclusion and reduced CD8-positive T cell infiltration ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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