New Cell Atlas Maps How the Newborn Heart Learns to Beat Like an Adult
By combining single-nucleus RNA sequencing with spatial transcriptomics, researchers have built a detailed spatiotemporal atlas of the postnatal mouse heart, ...
Tag: Spatial transcriptomics
Obesity Quietly Rewrites the Cellular Landscape of Colorectal Cancer Before Tumors Form
A dual-platform spatial transcriptomics study reveals that obesity reshapes colorectal cancer in two phases, first reprogramming healthy gut epithelium and ...
AI Maps a Hidden Neutrophil Niche in Lung Cancer and Flags a New Drug Target
A deep learning pipeline integrating single-cell and spatial transcriptomics has revealed an OSM-primed neutrophil niche that sustains aggressive mesenchymal tumor ...
New Computational Framework Tracks Cell Migration Across Space and Time
Researchers have developed a computational framework that integrates time-series single-cell RNA sequencing with spatial transcriptomics to reconstruct spatiotemporal cell-type redistribution ...
Graph Transformer Puts Rare Cell States on the Map in Single-Cell Data
A new heterogeneous graph transformer called scFormer connects cells through their most specific genes rather than their most similar neighbors, ...
New spatial transcriptomics method maps RNA isoforms across primate brain cells
For two decades, neuroscientists have been building ever finer maps of gene activity in the brain, charting which genes switch ...
DREAMS Maps Spatial DNA and RNA Modification Landscapes
A new method reported in Nature Cell Biology is offering scientists an unusually detailed view of how chemical modifications are ...
Experts develop consensus approach for spatially aware clustering beyond benchmarking
Spatial biology has created a problem that conventional clustering benchmarks were never designed to solve. In technologies such as spatial ...
Spatial Transcriptomics Reveals Histology-Linked Growth Patterns in Colorectal Liver Metastases
A new study is turning the microscopic “how it grows” question in colorectal cancer liver metastases into a measurable molecular ...
Nanoneedle Arrays Enable Sequencing-Free Spatial Profiling of Fresh Tissue Regulation
A team of researchers has unveiled a sequencing-free, amplification-free strategy for mapping gene regulation directly in space, tackling key bottlenecks ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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