Dual-Branch AI Framework CrossBranch Sharpens Cell-Type Maps Across Omics Data
A new dual-branch deep learning framework called CrossBranch improves the estimation of cell-type composition from bulk, proteomic, and spatial omics ...
Tag: Single-Cell RNA Sequencing
Aging Immune Cells May Undermine a Promising Cancer Therapy, Review Warns
A new review argues that immune aging and manufacturing stress, not just tumor biology, explain why gamma-delta T cell cancer ...
Single-Cell Map Reveals Vascular Barrier That Predicts BCG Failure in Bladder Cancer
A stage-spanning single-cell atlas of bladder cancer identifies a CXCR4-positive vascular-immune barrier at the T1 stage that excludes T cells ...
New AI Framework Predicts How Single Cells Choose Their Fates
A new physics-in neural network framework called GRNvelo unifies gene regulatory network dynamics with cell population behavior, accurately reconstructing cell ...
Single-Cell Map Reveals Five Macrophage States Behind Chemotherapy Resistance in AML
Single-cell RNA sequencing of post-chemotherapy AML bone marrow has identified five macrophage polarization states whose abundance tracks with treatment response ...
How Plants Rewind Their Cells: The Molecular Secrets of De Novo Organogenesis
A new review maps how hormones, gene networks, and epigenetic marks allow mature plant cells to revert to a pluripotent ...
AI Counts Tumor Buds in Colon Cancer Slides, Offering a New Prognostic Edge
A semi-supervised deep learning system called TBMNet accurately quantifies tumor budding in colorectal cancer slides and reveals molecularly distinct budding ...
New AI tool maps single cells onto tissue space with unprecedented precision
A new deep learning framework called SCmapST uses a seeded matches strategy to map single-cell gene expression data onto spatial ...
Cancer Cells Defy Quiescence Doctrine as MYC Drives a Proliferative Chemoresistance Program
A sweeping integrated genomics study reveals that chemotherapy-resistant tumors across multiple cancer types share a hyperproliferative, MYC-driven state, identifying the ...
Scientists Map Hidden Diversity in Stem Cells of a Remarkably Regenerative Marine Colony
A new study of the colonial cnidarian Hydractinia symbiolongicarpus shows that its adult pluripotent stem cells are transcriptionally and morphologically ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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