Antifungal liver injury study pinpoints KDR as shared hepatotoxicity target
A retrospective cohort of 199 pulmonary mycosis patients on triazole antifungals identified baseline liver enzymes and immunocompromised status as risk ...
Tag: Single-Cell RNA Sequencing
AI and Omics Converge to Decode the Gene Regulatory Logic of the Brain
A new Brain Informatics review traces how AI methods, from co-expression statistics to causal graph neural networks and foundation models, ...
Oxidative Stress Gene Signature Flags Prostate Cancer Recurrence Risk
A LASSO-based risk score built from oxidative stress-related genes predicts biochemical recurrence in prostate cancer, with LAMP5 knockdown reducing PC3 ...
Senescent Cells Play Both Hero and Villain in Muscle Repair, Review Finds
A new review in Cell Regeneration explains why transient senescent cells support muscle repair while persistent senescence in aged or ...
Tumor TNF-α Drives CCL4-Producing Neutrophils Linked to Immunotherapy Resistance in Lung Cancer
A new study links tumor-derived TNF-α, CCL4-high tumor-associated neutrophils, and suppressed T-cell activity to immunotherapy resistance in non-small cell lung ...
CD34+ Telocytes Drive Angiogenesis and Wound Healing Through Sema3c Signaling
A mouse study reports that CD34+ telocytes promote angiogenesis and wound healing by signaling to endothelial cells through Sema3c and ...
Tiny transparent fish yields first whole-body single-cell atlas of an adult vertebrate
Whitehead Institute researchers profiled more than 600,000 cells to build the first whole-body single-cell transcriptome atlas of an adult vertebrate, ...
Massive Single-Cell Map Reveals How Rare and Common Gene Variants Steer Immunity
Phase 1 of the TenK10K consortium maps common and rare genetic variants affecting gene expression across 28 immune cell types ...
Macrophage TRPV1 Loss Worsens Diet-Driven Colitis and Gut Fibrosis in Mice
Deleting Trpv1 in myeloid cells worsened inflammation, fibrosis and barrier dysfunction in mice with high-fat diet-exacerbated chronic colitis, via a ...
After Brain Injury, Astrocytes Ship Mitochondria to Struggling Neurons
A mouse study of traumatic brain injury found that astrocytes increase mitochondrial transfer to neurons via extracellular vesicles, a response ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!