Patient-derived stem cells and organoids open a new window on Moyamoya disease
A new review maps how patient-derived induced pluripotent stem cells and three-dimensional vascular and neurovascular organoids are transforming Moyamoya disease ...
Tag: Single-Cell RNA Sequencing
Tire Rubber Pollutant 6PPD-Quinone Linked to Erectile Dysfunction Through HIF-1α/eNOS/NO Axis
A new multi-omics and in vivo study shows that the tire-derived pollutant 6PPD-quinone impairs erectile function in rats by activating ...
Fish Guts Reveal Ancient Origins of Antibody Factory Structures
Researchers have discovered inducible germinal center-like structures in the gut of common carp, showing that sophisticated mucosal antibody responses evolved ...
Dual autoencoder framework sharpens single-cell clustering accuracy
A new deep clustering method, scDAEC, combines two autoencoders and multi-head attention to untangle noisy single-cell RNA sequencing data, outperforming ...
Single-Cell Study Pinpoints OTUD7B as a Master Switch Behind Pancreatic Cancer’s Defenses
A multiomics study identifies the deubiquitinase OTUD7B as a central driver of epithelial remodelling, mitochondrial reprogramming, and immune suppression in ...
Silenced Thyroid Gene CRABP1 Signals Aggressive Cancer Cells, Study Finds
A single-cell and epigenetic study links loss of the retinoid-binding protein CRABP1 to an invasive malignant epithelial cell state in ...
GenPerturb turns Perturb-seq data into sequence-grounded maps of gene regulation
Perturb-seq has become one of the most information-dense formats in functional genomics, combining single-cell RNA sequencing with pooled genetic or ...
New AI Framework Maps Drug Sensitivity Down to Individual Cells in Bulk Tumor Samples
A new two-step machine-learning framework called CLIMB and CLIFF computationally deconvolves bulk RNA-seq and drug sensitivity data into cell-type and ...
Small Set of Genes Drives Most Bias Between 3′ and 5′ Single-Cell RNA Sequencing Protocols
A systematic analysis of matched 3-prime and 5-prime single-cell RNA sequencing data shows that protocol-dependent expression bias is confined to ...
Single-Cell Atlas Maps the Inflammatory Immune Landscape of Biliary Atresia Livers
A single-cell RNA sequencing atlas of biliary atresia livers reveals expanded pro-inflammatory neutrophil subsets, activated cytotoxic lymphocytes, and injured endothelial ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!