Single-Cell RNA Sequencing Reshapes Liver Cancer Research, Global Analysis Reveals
A comprehensive bibliometric analysis of 979 publications reveals how single-cell RNA sequencing has evolved from cell cataloging to a dynamic, ...
Tag: Single-Cell RNA Sequencing
TET2 Emerges as Genetic Switch Driving Inflammatory Monocytes in Asthma
A new study identifies TET2 as an m6A-regulated gene that drives inflammatory monocyte activation in asthma through ALKBH5-mediated RNA demethylation ...
SOX9 Acts Early to Rewire Hippo–YAP/TAZ Signaling as Glioblastoma Cells Turn Stem-Like
New research shows that the transcription factor SOX9 primes Hippo–YAP/TAZ pathway rewiring during a narrow early window of stemness acquisition ...
Galectin-9 Emerges as a Key Driver of Immune Evasion in Cervical Cancer Progression
A multi-omics study traces cervical carcinogenesis from normal tissue to invasive cancer and identifies galectin-9-driven immune evasion as a promising ...
Gut Bacteria to Lung Damage: Single-Cell Map Reveals How a Traditional Mineral Medicine Turns Toxic
Single-cell transcriptomics, metabolomics, and microbiome sequencing reveal that high-dose Haematitum triggers gut dysbiosis that silences anti-inflammatory macrophage PPAR signaling, unleashes ...
Scientists Turn Single-Cell Data Into Personalized Immune Cell Designs for Breast Cancer
A new computational pipeline translates single-cell immune fingerprints from triple-negative breast cancer patients into ranked engineering recommendations for synthetic immune ...
Non-Classical Monocytes Linked to Immune Suppression in Tuberculosis Treatment Non-Responders
Single-cell RNA sequencing of tuberculosis patients reveals that non-responders to treatment carry expanded, terminally differentiated non-classical monocytes with dysregulated IL16 ...
Tumor Vesicles Loaded with SPP1 Rewire Fibroblasts to Shield Lung Cancer from Immunity
New research shows that lung adenocarcinoma cells package the protein SPP1 into extracellular vesicles to reprogram fibroblasts into an MMP11-positive ...
Liver Macrophages Carrying Apolipoprotein E Act as a Molecular Brake That Drives T Cell Exhaustion and Preserves Transplant Tolerance
A specialized APOE-producing Kupffer cell population in transplanted livers restrains rejection by driving attacking CD8-positive tissue-resident memory T cells into ...
Newly Discovered Trypsinogen Variants Drive Immune Responses in IgG4-Related Disease
Researchers identified novel PRSS1 trypsinogen variants in IgG4-related disease tissue and linked them to M2 macrophage-driven type 2 immune responses.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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