Tumor cell program tied to lymphatic responses in aggressive thyroid cancer
A multi-omics study links an extracellular matrix-associated epithelial state and a SERPINA1–SOX4–FN1 molecular axis to lymphatic endothelial responses in papillary ...
Tag: Single-Cell RNA Sequencing
Single-cell atlas reveals inflammatory monocyte state tied to WTAP in healthy lungs and COPD
A single-cell atlas of healthy and COPD lung tissue identifies an HSPA1B-positive inflammatory monocyte state whose transcriptional program is associated ...
Machine Learning Study Links ENTPD5 to Radioresistance in Liver Cancer
An integrated machine-learning and single-cell study identifies ENTPD5 as a context-dependent candidate marker of radioresistance in hepatocellular carcinoma, with prognostic ...
Single-cell map reveals immune-fibrotic imbalance driving COPD
A single-cell RNA sequencing analysis of 101,009 cells identifies 17 cell subtypes and reveals reduced macrophage and fibroblast signaling alongside ...
Sepsis Study Points to THBS1 as a Myeloid-Linked Marker of Poor Outcomes
An integrated transcriptomic and computational study identifies THBS1 as a candidate myeloid-associated molecule linked to inflammatory dysregulation and poorer survival ...
Beyond the classics: why biology’s future lies in non-traditional model organisms
A BMC Biology editorial argues that falling costs in sequencing, imaging and gene editing are freeing biologists to study any ...
Single-Cell Map of Androgen Receptor States in Resistant Prostate Cancer
An exploratory single-cell RNA sequencing study maps androgen receptor-associated cellular states in castration-resistant prostate cancer while explicitly avoiding AR-V7 classification ...
Gastric Cancer’s Public Data Boom Produces Gene Lists, Not Clinical Answers, Review Warns
A sweeping methodological review published in Frontiers in Oncology argues that the explosion of public-omics research in gastric cancer has ...
Blood Protein Panel Flags Early Esophageal Cancer with High Accuracy in Chinese Case-Control Study
A machine-learning model based on six serum proteins diagnosed esophageal squamous cell carcinoma with AUCs of 0.932 and 0.968 in ...
Eight-Gene Signature Ties Immune Landscape to Gastric Cancer Survival
An integrated transcriptomic and tissue-level study links an eight-gene risk score and the immune regulator RGS1 to survival in gastric ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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