Single RNA Letter Swap Turns a Thyroid microRNA From Tumor Suppressor Into Cancer Driver
Researchers show that ADAR2-mediated A-to-I RNA editing switches miR-376a-3p from a tumor suppressor to an oncogene in papillary thyroid cancer ...
Tag: RNA modification
RNA Chemical Tag Drives Endometrial Cancer Through a DNA Repair Protein, Study Finds
New research reveals that the RNA modification reader ALYREF drives endometrial cancer progression by stabilizing XRCC6 mRNA and activating Wnt/β-catenin ...
Hidden RNA Tags May Steer Lung Cancer Growth, Treatment Response, and Survival
A sweeping review reveals how the RNA modification N6-methyladenosine orchestrates lung cancer progression, drug resistance, immunotherapy response, and survival prediction.
Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
RNA Modification and Cell Death Genes Point to New Prognostic Tool for Ovarian Cancer
Researchers built a machine learning gene signature combining RNA modification and programmed cell death biology that predicts survival and immunotherapy ...
Chemical Tags on Viral RNA Emerge as a Battleground Between Plants and Pathogens
A new review details how the m6A RNA modification acts as both an antiviral defense and a viral exploitation tool ...
RNA Chemical Tag ac4C Reveals Fibroblast Signal That Drives Colorectal Cancer Aggression
A comprehensive profiling study links the ac4C RNA modification to aggressive colorectal cancer and identifies CERCAM in cancer-associated fibroblasts as ...
RNA Tag METTL3 Drives Lung Scarring by Destabilizing a Key Fat-Droplet Protein
New research shows that the RNA methyltransferase METTL3 promotes lipid deposition and pulmonary fibrosis by destabilizing the messenger RNA of ...
Chemical Tags on RNA Take Center Stage in Cancer’s Growth and Immune Evasion
A new review in Molecular Cancer details how the abundant RNA mark m6A drives cancer growth, immune evasion and treatment ...
Hypoxia Rewires RNA Methylation to Drive Pancreatic Neuroendocrine Tumor Growth
A new study reveals how low oxygen strips m6A methylation marks from tumor cell RNA, unleashing a signaling cascade that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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