Chemical Tags on mRNA Keep Pancreatic Alpha Cells From Turning Into Beta-Like Cells
New research shows that the mRNA modification m6A, installed by METTL14, is required to maintain pancreatic alpha-cell identity and prevent ...
Tag: RNA modification
Hidden Protein Bosses the Cleanup Crew That Keeps Lupus at Bay
Scientists have discovered that the protein FAM76B regulates macrophage clearance of dying cells through an m6A-ISG15-autophagy pathway whose failure drives ...
Short RNA Reads Underestimate A-to-I RNA Editing, Long-Read Sequencing Reveals
A new study shows that short-read RNA sequencing systematically underestimates A-to-I RNA editing levels compared with long-read cDNA sequencing, largely ...
Body Clock Protein BMAL1 Steers Stem Cells Into Neurons Through RNA Tagging
A new study in Genome Biology shows that the circadian factor BMAL1 is required for human embryonic stem cells to ...
METTL3 Emerges as a Molecular Hub Driving Tumor Immune Escape
A new review in the Journal of Translational Medicine details how the RNA methyltransferase METTL3 drives tumor immune escape through ...
Nsun5 Deficiency Weakens Myelin Integrity and Disrupts Sleep
Sleep loss is often treated as a problem of brain circuits, stress hormones or disrupted daily rhythms. A new study ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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