Tag: retinal degeneration

A five-year NIH grant will fund Upstate cell research on how PRCD and KIAA1549 support photoreceptor outer-segment formation implicated in ...

Researchers report a non-viral, OCT-guided method using gold nanorods and a 980-nm laser to deliver the opsin MCO-020 to targeted ...

New research reveals how the gap junction protein connexin 36 is degraded in photoreceptor cells under excitotoxic stress, implicating autophagic, ...

The first comprehensive proteomic analysis of retinas from humanized sickle cell anemia mice reveals early downregulation of phototransduction and mitochondrial ...

An international trial led by University of Pittsburgh scientists found that an optogenetic gene therapy combined with light-projecting goggles was ...

New research shows that female mice lacking the protein quality-control gene Herc3 suffer faster retinal thinning, greater inflammatory activation, and ...

Researchers used directed evolution to create AAV5-AlyT, an adeno-associated virus variant that delivers genes efficiently to photoreceptors after minimally invasive ...

New research shows that the RNA methyltransferase METTL16 protects rod photoreceptors by safeguarding splicing fidelity, mRNA stability, and translation, and ...

A Chinese case report documents angioid streaks, an eye finding never before linked to spinocerebellar ataxia type 7, alongside striking ...

A new Gene Therapy review charts how mutation-agnostic optogenetic gene therapy could restore vision in blind patients, while detailing the ...