Rab GTPase Blockers Fail to Dampen Adrenergic Contraction in Human Prostate Tissue
A study in human prostate tissues finds that inhibitors of the Rab GTPases Rab7 and Rab27 fail to consistently alter ...
Tag: receptor trafficking
Cellular Recycling Routes Reshape How Hormone Receptors Send Their Signals
A new computational model shows that a small pool of internalized follicle-stimulating hormone receptors can drive outsized endosomal signaling, revealing ...
Insulin Receptor Signaling Is Not One Pathway: Engineered Mimetics Reveal a Programmable Network
A new review argues that insulin receptor signaling is a programmable, context-dependent network that engineered mimetics can selectively retune across ...
Opioid Drugs Act as Molecular Chaperones to Reshape Receptor Trafficking
New research shows that naltrexone, naloxone, morphine, and fentanyl act as pharmacological chaperones that expand endoplasmic reticulum exit sites and ...
Orphan Bitter Taste Receptors Found on Cell Surfaces, Hinting at Hidden Functions
A new tagging method reveals that orphan and supposedly nonfunctional human bitter taste receptors reach the cell surface, suggesting they ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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