Adult Toxocara canis secretome mapped: 468 proteins reveal diagnostic targets
The first comprehensive proteomic analysis of excretory-secretory proteins from adult Toxocara canis identifies 468 proteins dominated by TES-26 antigens, C-type ...
Tag: Proteomics
Why Some Dairy Cows Keep More Urea in Their Milk: Clues From the Kidney Proteome
A kidney proteome and clearance study of Holstein dairy cows finds that high milk urea stems from altered local solute ...
Testican-2: from glomerular activity to circulating biomarker
Higher circulating Testican-2 tracks better kidney function and milder glomerular damage, but researchers warn that plasma levels may not yet ...
Blood proteins linked to prostate cancer risk over decade before diagnosis
A prospective EPIC-based study found blood-protein associations with prostate cancer more than 15 years before diagnosis, including markers linked to ...
Hybrid Machine Learning Pipeline Brings Transparency to Bacterial Selenoprotein Discovery
A new hybrid pipeline called SelCysML combines interpretable machine learning with BLAST-based validation to identify and functionally annotate bacterial selenoproteins ...
Plasma Protein Signatures Predict Rheumatoid Arthritis Years Before Symptoms Appear
A UK Biobank study of 47,537 people identified 213 plasma proteins linked to rheumatoid arthritis onset and built a deep ...
Synthetic Peptide IL15.3 Calms Inflamed Immune Cells on Multiple Fronts
The synthetic antimicrobial peptide IL15.3 reduced inflammatory signaling in LPS-stimulated macrophages through coordinated transcriptional and proteomic changes, with low cytotoxicity ...
Blood Proteins Predict ALS Years Before Symptoms Strike
A large prospective UK Biobank study of 52,584 adults identified nine plasma proteins, led by neurofilament light chain, that predict ...
Copper cell death splits into two distinct routes converging on mitochondria
A preclinical study in Molecular Cancer reports that elesclomol and neocuproine trigger mechanistically distinct, FDX1-dependent and FDX1-independent forms of copper-driven ...
Why Metformin Works Differently in Different Bodies: Multi-Organ Molecular Maps Point to an Answer
A tissue-resolved multi-omics study in obese diabetic gerbils links metformin's variable glycemic effects to distinct molecular programs in liver, muscle, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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