Hidden Peptides in Non-Coding RNAs Reshape Cardiovascular Biology
A new review argues that some non-coding RNAs produce functional peptides and act as bifunctional regulatory units in cardiovascular disease.
Tag: Proteomics
LC–MS/MS emerges as the workhorse of modern drug development
A new review maps how liquid chromatography–tandem mass spectrometry now quantifies drugs, metabolites, genotoxic impurities and proteins across every stage ...
IGF-I Gene Therapy Reshapes the Proteome of Cartilage-Forming Stem Cells from Osteoarthritis Patients
A new proteomic study maps how rAAV-mediated IGF-I gene transfer alters protein expression in bone marrow stromal cells from osteoarthritis ...
Proximity Labeling Maps the Protein Neighborhoods of Two Amyloid Forms in Alzheimer’s Hippocampus
Proximity labeling in postmortem human hippocampus reveals that pyroglutamate-modified Aβ carries an expanded, variant-specific set of neighboring proteins in Alzheimer's ...
Imaging, Genes and Proteins Combine to Predict Liver and Pancreas Disease Risk
A UK Biobank study of 38,844 participants shows that integrating MRI-derived liver and pancreas traits with genetic variants and proteomic ...
Multi-omics study links kwashiorkor to tissue remodeling and lipid disruption
A matched multi-omics study of 180 children in Niger identifies extracellular matrix proteins and sphingolipid disturbances as molecular signatures of ...
Scientists identify Tollip as a brake on plasma membrane repair
A new study identifies Tollip as a conserved negative regulator of ESCRT-III-mediated plasma membrane repair, showing that the protein balances ...
Calprotectin emerges as top plasma biomarker separating acute joint implant infection from aseptic failure
A Danish proteomics study found the calprotectin subunits S100A8 and S100A9 to be the most significantly elevated plasma proteins in ...
Blood Proteins Linked to Heart Imaging Signatures and Disease Risk in Large UK Biobank Study
A UK Biobank study linked 681 blood proteins to cardiac MRI phenotypes and used genetic analysis to prioritize potentially causal ...
Neuropsychiatric Symptoms in Alzheimer’s Disease Linked to Amyloid and Heat Shock Proteins
A cross-sectional ADNI study of 713 participants links neuropsychiatric symptoms to lower CSF amyloid-β42 and identifies heat shock protein pathways ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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