Tag: protein stability

A study published in Cellular Oncology reveals that OTUD1 stabilizes SLC7A11 via deubiquitination to suppress ferroptosis and promote lenvatinib resistance ...

A compact energy-based neural network called LEEN predicts protein stability changes from single amino acid substitutions using roughly 2 to ...

Researchers developed ESMTmP, a multiscale multitask learning model that predicts protein melting temperatures with reduced error and order-consistent outputs.

Overlapping deep mutational scanning experiments were fused into a consensus variant soundness score that trained ESMRank, a sequence-based learning-to-rank model ...

ZNF207 stabilizes the glutamine transporter ASCT2 by blocking SPOP-driven ubiquitin-proteasome degradation, sustaining AKT/mTORC1 signaling in hepatocellular carcinoma cells.

A computational analysis of more than 1,000 FOXE1 variants identified 37 high-risk candidates, most predicted to reduce protein stability, with ...

A new plasma-derived fibrinogen concentrate manufactured with an added UV-C irradiation step retained near-full activity, high purity and five-year stability ...

A review describes how RXLR effectors from the potato late blight pathogen target multiple immune and cellular processes that support ...

A new study shows that sugar-based chemical interactions, rather than molecular crowding size, help the glycolytic enzyme PFKP stay active ...

By swapping every valine in the protein GB1 for fluorinated analogues, researchers used fluorine-19 NMR, three-bond coupling constants and gamma ...