Commentary frames tumor microenvironment as a driver of metastasis and resistance
A 2026 commentary proposes that metabolic plasticity, stromal reprogramming and immune-metabolic competition create an adaptive tumor ecosystem that can promote ...
Tag: precision oncology
Turning Off a Cancer Cell’s Survival Switch: How NRF2 Controls Ferroptosis in Targeted Therapy
A new review details how the NRF2 transcription factor shields cancer cells from iron-dependent ferroptotic death and how natural and ...
AI Reads Routine CT Scans to Predict Bladder Cancer HER2 Status Without a Biopsy
A machine learning model applied to routine CT urography scans can non-invasively predict HER2 status in bladder cancer, potentially guiding ...
AI Reads Lung CT Scans to Predict Drug Resistance Before Treatment Begins
A Chinese research team combined delta-radiomics from CT scans with clinical data and SHAP-based machine learning interpretation to predict the ...
Ovarian Cancer Cells Depend on USP15 Enzyme, Offering a Sharper Therapeutic Target
UMBC researchers found that ovarian cancer cells depend heavily on the enzyme USP15, and reducing it slows tumor growth, disrupts ...
Hidden inherited cancer risks surface in routine tumor sequencing, oncologists warn
The practical framework outlined by Zhang and Madlensky arrives at a moment when the infrastructure of precision oncology is being ...
Glowing RNA Molecules Light Up Cancer Cells for Precision Oncology
A new review in Molecular Biology Reports surveys how fluorogenic RNA aptamers, engineered RNA strands that switch on fluorescence upon ...
Hidden Chemoresistant Cells Reveal Which Children With Leukemia Are Most at Risk
A single-cell transcriptomic analysis of paired diagnosis and relapse samples identifies chemoresistant cell populations that, combined with cytogenetics and measurable ...
Tiny Tumor Fragments From Needle Biopsies Predict Which Breast Cancer Drugs Will Work
Patient-derived microtumors grown from core needle biopsies as small as a few cubic millimeters of tissue successfully predicted breast cancer ...
Hidden Gene Variants May Explain Why Chemotherapy Hits Some Patients Harder Than Others
A new review links inherited variants in ABCB1, ABCC1, and ABCG2 drug transporter genes to differences in chemotherapy and targeted ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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