Long-Read DNA Sequencing Uncovers Hidden Cancer Drivers Missed by Standard Tests
University of Michigan researchers used long-read nanopore sequencing to resolve hidden cancer-driving alterations in tumors and to trace the origin ...
Tag: precision oncology
Review Connects Circadian Clock Disruption With Cancer Metabolism and Progression
A 2026 review links disrupted circadian clock genes with altered cancer metabolism, cell survival, and pathways implicated in tumor progression.
Global tumor board maps investigational options for glioblastoma with MDM2 and EGFR amplifications
A new Oncotarget case report details how the WIN Consortium's international molecular tumor board evaluated investigational EGFR, MDM2, CDK4/6 and ...
Blood lncRNA RIME test refines who benefits from first-line ESCC immunochemotherapy
An exploratory multicenter biomarker analysis shows that pretreatment plasma lncRNA RIME, especially when combined with PD-L1, distinguishes patients with advanced ...
Editorial: Mechanisms of drug resistance in cancer: overcoming barriers with novel pharmacological strategies
An editorial summarizing eight contributions describes cancer drug resistance as an adaptive process involving genetic, epigenetic, metabolic, signalling and microenvironmental ...
Retrospective Chinese NSCLC study links compound EGFR mutations to poorer TKI response
A retrospective single-center analysis of 452 Chinese patients with non-small cell lung cancer associated compound and co-occurring EGFR mutations with ...
Extracellular Vesicles Could Map the Location of Metastatic Cancer
A proposed liquid-biopsy strategy combines tumor-associated and organ-associated markers on circulating extracellular vesicles to infer metastatic sites, but it remains ...
Research report: Protein acylation in cancer: from regulatory networks to precision therapeutics
A peer-reviewed review examines protein acylation as a link among cancer metabolism, tumor plasticity, therapeutic resistance and proposed biomarker-guided treatment ...
Research report: Revisiting Ehrlich carcinoma in the era of precision oncology: bridging classical models with modern systems biology
A 2026 review proposes modernizing the murine Ehrlich carcinoma model with multi-omics, single-cell profiling, CRISPR experiments and RISC-centered analysis while ...
Whole-genome sequencing of paired prostate cancer cell cultures from 10 African American men reveals recurrent DNA-repair alterations
A prospective laboratory study that sequenced matched tumor and non-malignant primary cultures from 10 African American men with prostate cancer ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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