Tiny Tumor Fragments From Needle Biopsies Predict Which Breast Cancer Drugs Will Work
Patient-derived microtumors grown from core needle biopsies as small as a few cubic millimeters of tissue successfully predicted breast cancer ...
Tag: precision oncology
Hidden Gene Variants May Explain Why Chemotherapy Hits Some Patients Harder Than Others
A new review links inherited variants in ABCB1, ABCC1, and ABCG2 drug transporter genes to differences in chemotherapy and targeted ...
Induced Pluripotent Stem Cells Take Aim at Cancer Prevention, Therapy, and Tumor Modeling
A new review highlights how induced pluripotent stem cells are being engineered into immune cells, cancer vaccines, and tumor models ...
How Breast Cancer Cells Outsmart Hormone Therapy—and the New Drugs Fighting Back
A new review details how ESR1 mutations, bypass signaling, and cell-cycle escape drive endocrine resistance in the most common breast ...
Kinase Inhibitors Beat Aggressive Skin T-Cell Lymphomas—Until Tumors Learn to Fight Back
A new review maps how aggressive cutaneous T-cell lymphomas develop resistance to targeted kinase inhibitors, revealing gatekeeper mutations and cross-kinase ...
AI Reads Tumor Slides to Predict Melanoma Gene Mutations, Offering Faster Targeted Therapy Triage
A new study shows that AI models trained on routine pathology slides can predict BRAF mutation status in melanoma patients ...
Fear, Distrust and Distance: What 131 Studies Reveal About Why Cancer Patients Avoid Clinical Trials
A scoping review of 131 studies finds that fear, distrust, logistical burdens and poor information, rather than unwillingness, keep most ...
Two PET scans may outsmart a single biopsy in predicting aggressive neuroendocrine cancer outcomes
A new study shows that discordant lesions on dual-tracer FDG and FAPI PET/CT strongly predict shorter progression-free survival in aggressive ...
Fruquintinib May Edge Ahead in KRAS-Mutant Colorectal Cancer, But No Clear Winner Yet
A Bayesian network meta-analysis of ten randomized trials finds that fruquintinib, regorafenib, and TAS-102 all extend survival in refractory metastatic ...
Whole-genome scan of 1,001 prostate cancers reveals hidden drivers and four risk oncotypes
A whole-genome analysis of 961 primary prostate tumours reveals recurrent driver alterations, enhancer hijacking at solute carrier genes, and four ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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