Proteomic Aging Clocks Face Their First Real-World Test in a Clinical Trial
For the first time, six proteomic aging clocks have been deployed as readouts in a clinical trial, revealing more about ...
Tag: plasma proteomics
Massive Blood RNA Atlas Maps Molecular Fingerprints of 98 Human Diseases
Researchers have built a whole blood transcriptomics atlas spanning 4,444 samples and 98 health conditions, and show that integrating RNA ...
Blood Tests of Ageing Face Off: Brain Scans and Epigenetic Clocks Beat Organ Clocks at Predicting Death
A 16-year Scottish cohort study finds that while proteomic organ clocks predict mortality, epigenetic, brain imaging, cognitive and lung function ...
Chemical Tags on Blood Proteins Reveal a New Window Into Alzheimer’s Disease
Researchers at the University of Tokyo have produced the first map of lysine acetylation marks across plasma proteins in Alzheimer's ...
Antibody Fingerprint in Blood Reveals Why Plasma Proteomes Differ Between People
A year-long dual-laboratory study of 51 healthy donors shows that immunoglobulin subclass levels are remarkably stable within individuals yet vary ...
Budget Mass Spectrometers Can Match the Big Machines in Plasma Proteomics, Study Finds
A new study shows that widely accessible mass spectrometry instruments can reliably distinguish the performance of seven plasma preparation platforms, ...
Blood Protein Signature and Immune Target Show Promise for Earlier ARDS Diagnosis and Treatment
A seven-protein immunoproteasome signature detected in blood accurately diagnosed ARDS in clinical cohorts, while blocking the subunit PSMB8 reduced lung ...
Proteomic Aging Clocks Enter the Clinic in Landmark Phase 2a Geroprotection Trial
Proteomic aging clocks have been integrated into a phase 2a clinical trial, enabling simultaneous assessment of geroprotective effects within an ...
AI Framework Turns Blood Protein Data Into Ageing Drug Target Hypotheses
A new six-stage computational framework called Protein Expression Net converts plasma proteomic ageing signatures from UK Biobank data into prioritized, ...
Proteomics identifies two reproducible sepsis-associated kidney injury subtypes with distinct outcomes
A new study published in Nature Communications reports that sepsis-associated acute kidney injury, one of the most dangerous complications of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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