Tag: PI3K/AKT/mTOR pathway

Elevated TBRG4 expression correlates with adverse clinicopathological features in prostate cancer and promotes tumor growth and cell invasion in experimental ...

A study of more than 53,000 participants and experimental animal models found that elevated circulating ANGPTL4 predicts chronic kidney disease ...

Researchers found that the intrinsic IRG1-itaconate axis in CD4+ T cells restrains allergic airway inflammation by dampening PI3K/Akt/mTOR signaling, with ...

A new review proposes a two-layer signaling network organizing female germline stem cell fate as a testable framework for staged ...

A new review details how ESR1 mutations, bypass signaling, and cell-cycle escape drive endocrine resistance in the most common breast ...

A new review in Cellular and Molecular Life Sciences maps the molecular pathways, immune microenvironment and AI-driven technologies that shape ...

A new mouse study shows that Panax ginseng relieves fatigue by reactivating the PI3K/AKT/mTOR pathway to suppress excessive autophagy and ...

New research shows that two Bifidobacterium breve strains metabolize the omega-3 fatty acid EPA into distinct bioactive metabolites that computational ...

A new preclinical study shows that the β-catenin/CBP inhibitor ICG-001 selectively kills endometrial cancer cells carrying both PIK3CA and CTNNB1 ...

A comprehensive review finds that the PI3K/AKT/mTOR signaling axis drives progression and therapy resistance in gastrointestinal cancers, but clinical success ...