Computer screen sifts animal peptides for breast cancer drug leads
A computational pipeline filtered about 1,500 animal-derived antimicrobial peptides down to three candidates that dock strongly against the breast cancer ...
Tag: peptide design
Host-derived peptide shows antiviral activity against herpes simplex virus type 1 in vitro
Scientists engineered an HVEM-derived peptide that blocked about sixty percent of HSV-1 infection in cell tests without toxicity.
Copper turns designer peptides into selective cancer-cell killers in lab tests
Researchers report that binding copper(II) ions to one of two designer peptides containing non-canonical amino acids markedly increased its cytotoxic ...
Computational Design Yields Chimeric LL-37/HNP-1 Peptide Candidate for Respiratory Co-Infections
A new computational study reports the design and in-silico evaluation of a chimeric antimicrobial peptide fusing LL-37 and HNP-1 domains ...
AI-guided design yields high-affinity nucleosome acidic-patch binders
A brief experimental study combined BindCraft peptide design with a refined FRET assay to identify high-affinity binders of the nucleosome ...
AI-Designed Peptides Take Aim at an Aggressive Liver Cancer Target
Using an AI-driven computational pipeline, researchers have designed and prioritized five peptide candidates that target the glypican-3 protein found on ...
Pep2Net Unifies Fragmented Peptide Databases With a Cross-Attention AI Model
A new Genome Biology study introduces Pep2Net, a platform combining a knowledge base built from 52 peptide databases with a ...
Network Science Reveals Why SARS-CoV-2 Binds Human Cells More Tightly Than SARS-CoV-1
A network-based analysis of molecular dynamics simulations shows that SARS-CoV-2 forms more robust connections with the human ACE2 receptor than ...
DyME: A New Engine Automates Thousands of Protein Simulations for Molecular Design
Researchers have developed DyME, an open-source platform that automates high-throughput mutagenesis, molecular dynamics simulation, and comparative analysis of thousands of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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