Small single-center study describes dinutuximab beta maintenance for high-risk neuroblastoma
A retrospective study of 13 children at one Chinese center reported 3-year maintenance-phase event-free survival of 69.2% and described adverse ...
Tag: pediatric cancer
EP300 Degradation and AKT Inhibition Slow Osteosarcoma in Preclinical Models
A PROTAC that degrades EP300 combined with AKT inhibition slowed tumor growth and extended survival in patient-derived osteosarcoma mouse models, ...
When Brain Tumors Keep Coming Back: Recurrence Intervals Shorten With Each Relapse
A retrospective study of 49 patients with multiply recurrent intracranial germ cell tumors reveals that relapse intervals shorten significantly with ...
Universal Psychosocial Screening Becomes Standard of Care in Pediatric Cancer
A two-year implementation study at a major children's cancer center shows that universal psychosocial screening across the pediatric cancer treatment ...
Three-Day Whole Genome Sequencing Transforms Childhood Cancer Diagnosis
A UK study shows rapid whole genome sequencing cuts pediatric cancer diagnosis time from six weeks to three days while ...
Blood Test Tracks Ovarian Reserve in Girls With Cancer From Diagnosis to Adulthood
A Swedish prospective study is tracking anti-Müllerian hormone levels in girls with cancer from diagnosis to age 25 to identify ...
Cancer Protein LGALS3BP Reshapes the Cargo of Neuroblastoma Extracellular Vesicles
New research links the secreted glycoprotein LGALS3BP to selective enrichment of microRNAs and the RNA-binding protein SRSF1 in neuroblastoma extracellular ...
Aberrant Antibodies That Cripple DNA Repair May Predict Childhood Cancer Years in Advance
Researchers in Norway found that children who later develop cancer carry unusual auto-antibodies against their own DNA repair proteins, suggesting ...
Trapping rogue DNA rings in micronuclei could disarm aggressive tumors
An international research team has shown that rings of extrachromosomal DNA lose their cancer-driving activity when trapped in micronuclei, a ...
Lactate Marks on Histones Drive Wilms Tumor Growth Through a Self-Reinforcing Genetic Loop
New research reveals that lactate-driven histone H3K18 lactylation activates a PSRC1/AKT/HIF-1α positive feedback loop that propels the malignant progression of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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