BK Virus Kidney Infection Shows Broad Immune Disruption in Transplant Patients
A combined transcriptomic and histological study of kidney biopsy tissue reveals widespread immune activation, checkpoint upregulation, and altered T-cell dynamics ...
Tag: PD-L1
Triple Therapy Shows Edge in Lung Cancer Lacking Targetable Mutations
A new network meta-analysis of five trials involving 2,452 patients finds that triple therapy combining immunotherapy, antiangiogenic antibodies, and chemotherapy ...
Immune-Boosted Chemo Cuts Death Risk by a Third in Advanced Esophageal Cancer, Landmark Analysis Finds
A revised meta-analysis of six phase III trials shows first-line PD-1 inhibitor plus chemotherapy reduces the risk of death by ...
How Sleep Apnea and Obesity May Quietly Fuel Cancer Growth
A new perspective in the International Journal of Obesity argues that obesity, obstructive sleep apnea, and cancer form an interconnected ...
Antibody-Drug Conjugate RC48 Ignites Ferroptosis to Rally Immune Cells Against HER2 Breast Cancer
New research shows the anti-HER2 antibody-drug conjugate disitamab vedotin kills breast cancer cells through ferroptosis, releasing danger signals that activate ...
Macrophage Exosomes Disarm Immune Cells and Fuel Ovarian Cancer Spread
A new study shows that exosomes released by tumor-associated macrophages carry PD-L1 that reprograms the metabolism of CD8-positive T cells, ...
Radiation Supercharges Natural Killer Cell Therapy Against Liver Cancer in New Study
New research shows that radiation can make liver cancer cells more visible to natural killer cells, boosting the effectiveness of ...
Two Novel PET Tracers Reveal Limits of PD-L1 Imaging in Advanced Lung Cancer
A head-to-head trial of two fluorine-18 PD-L1 PET tracers in advanced lung cancer found equal tumor uptake between the agents ...
AI Tells Doctors When It Is Unsure About Cancer Treatment Success
University of Washington researchers have built a decision support system that combines PET imaging, immune repertoire sequencing, and blood cytokines ...
Rare POLE P286R-Mutated Lung Cancer Shows Dramatic Response to Immunotherapy
A case report describes the first hepatoid adenocarcinoma of the lung harboring a POLE P286R mutation, which drove hypermutation, mismatch ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!