Immunotherapy Plus Chemoradiotherapy Triples Survival in Esophageal Cancer Study
A propensity score matched study from Taiwan finds that adding the immunotherapy drug nivolumab to definitive chemoradiotherapy tripled median overall ...
Tag: PD-L1
Transparent AI Model Hits 95% Accuracy in Choosing Immunotherapy for Head and Neck Cancer
Researchers in Leipzig corrected a hidden error in a Bayesian network and found the transparent AI model matched real tumor ...
Chemical Tags on RNA Take Center Stage in Cancer’s Growth and Immune Evasion
A new review in Molecular Cancer details how the abundant RNA mark m6A drives cancer growth, immune evasion and treatment ...
Radiomics Gives Doctors a Whole-Tumor Map Where Biopsies Only See a Point
A new review argues that radiomics should serve as a spatial context for biopsy-based biomarkers in head and neck cancer, ...
Chemoimmunotherapy Before Surgery Delivers Striking Survival Gains in Limited-Stage Small-Cell Lung Cancer
A retrospective real-world study found that neoadjuvant chemoimmunotherapy followed by surgery produced significantly longer overall survival and strong pathologic responses ...
How Stomach Bacteria Rewire Immune Checkpoints to Fuel Gastric Cancer
A new review explains how Helicobacter pylori virulence factors drive PD-L1 expression in gastric cancer through crosstalk among the NF-κB, ...
Tiny RNA Cluster Revealed as Master Switch Behind Lung Cancer Survival and Immune Evasion
Researchers at the University of Bern show that the miR105/767 microRNA cluster coordinates apoptosis, cell-cycle progression, and PD-L1 expression in ...
Jumping Genes May Ignite Immune Defenses in Stomach Cancers with DNA Repair Weaknesses
New research links LINE-1 retrotransposon overexpression and homologous recombination deficiency in gastric cancer to heightened immune pathway activation and potential ...
Open-Source Machine Learning Workflow Accelerates Discovery of Small-Molecule PD-L1 Cancer Inhibitors
Researchers have built a fully open-source KNIME machine-learning workflow that curates thousands of PD-L1 bioactivity records and reliably predicts inhibitor ...
RNA Editing Enzyme ADAR1 Emerges as Key Switch That Turns Cold Bladder Tumors Hot
Researchers found that inhibiting the RNA editing enzyme ADAR1 reprograms the immunosuppressive tumor microenvironment of bladder cancer and sensitizes it ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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