RBM15 Drives Non-Small Cell Lung Cancer Immune Evasion via RNA Methylation
Researchers have demonstrated that the RNA methyltransferase subunit RBM15 drives immune evasion in non-small cell lung cancer cell models by ...
Tag: PD-L1
Tumor Microenvironment and PD-L1 Shape Immune Checkpoint Combinations in Triple-Negative Breast Cancer
A review highlights how the tumor microenvironment and PD-L1 shape immune checkpoint combination therapy in triple-negative breast cancer.
HMGA1 Links Lactate Signaling to Immunosuppressive Pathways in Hepatocellular Carcinoma
Single-cell and laboratory analyses identify HMGA1 as a candidate regulator connecting lactate metabolism to regulatory T cell-associated immune responses in ...
Review Evaluates lncRNA H19 Links to Immune Checkpoints in Gastrointestinal Cancers
A comprehensive narrative review published in Clinical and Experimental Medicine has synthesized the experimental and clinical evidence examining whether the ...
Review Finds No m6A Regulatory Axis Fully Validated in Bladder Cancer
A review in Discover Oncology reports that no m6A RNA modification axis has achieved site-resolved validation in immune-competent orthotopic bladder ...
Elevated CD112 Predicts Poorer Cervical Cancer Survival in Multi-Database Analysis
A multi-database and laboratory evaluation identifies immune checkpoint CD112 as an independent prognostic biomarker linked to reduced survival in cervical ...
RFX2 Loss Promotes Immune Escape in Lung Adenocarcinoma via Hippo Signaling
Downregulation of the transcription factor RFX2 promotes immune escape and tumor progression in lung adenocarcinoma by suppressing RASSF1 and reducing ...
Immune checkpoint inhibitors show lower peripheral but higher central neurological risks in lung cancer trials
A systematic review and meta-analysis of lung cancer immunotherapy trials finds lower peripheral but higher central neurological immune-related adverse event ...
Review links hypoxia factors to immune evasion in head and neck cancer
A review in Cancer Cell International details how hypoxia-inducible factors drive immune evasion in head and neck squamous cell carcinoma, ...
Macrophage PD-L1 Loss Reduces CD80 Surface Expression
A new study in Frontiers in Oncology reveals that PD-L1 deletion or blockade in macrophages consistently reduces surface levels of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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