Genetic and Global Burden Data Point to Lipid-Immune Targets in Gynecological Cancers
A combined analysis of global disease data and Mendelian randomization identifies lipid species and immune traits with putative causal links ...
Tag: PD-L1
Air Pollutants and Tobacco Carcinogens Drive Colon Cancer via Metabolic Reprogramming
Researchers uncover how fine particulate matter and tobacco carcinogens cooperate with glucose to accelerate colorectal cancer growth through macrophage-driven immune ...
Lactate-Driven Regulatory B Cells Suppress Immunity in Lung Cancer, Mouse Study Finds
A mouse and early human study links tumor-derived lactic acid to a ROS-producing regulatory B cell subset that suppresses T ...
TAM receptors and STAT–SOCS signaling shape the immune landscape of thymic epithelial tumors
A new integrative analysis links TAM receptor and STAT–SOCS signaling to immune infiltration patterns in thymic epithelial tumors.
MRI signal patterns hint at immune landscape of liver cancer in exploratory study
An exploratory study found that arterial wash-in on dynamic contrast-enhanced MRI was inversely correlated with CD3-positive stromal lymphocyte infiltration in ...
Tumor TNF-α Drives CCL4-Producing Neutrophils Linked to Immunotherapy Resistance in Lung Cancer
A new study links tumor-derived TNF-α, CCL4-high tumor-associated neutrophils, and suppressed T-cell activity to immunotherapy resistance in non-small cell lung ...
Rare Sarcoma Arising From Castleman Disease Tied to Pemphigus and Poor Survival
A six-case retrospective study found follicular dendritic cell sarcoma arising from Castleman disease was frequently complicated by paraneoplastic pemphigus and ...
Immune Cells Skew Toward Inflammation in Children With Newly Diagnosed ITP
A case-control study of 32 children with newly diagnosed immune thrombocytopenia found a pro-inflammatory shift in circulating monocyte-macrophage polarization and ...
Lactate Drives Immune Evasion in Pancreatic Cancer via TRMT6-SIRT5 Axis
A new study reports that lactate in the pancreatic tumor microenvironment promotes metabolic reprogramming and PD-L1 upregulation through the TRMT6-SIRT5 ...
AI pathology scoring flags longer survival on pembrolizumab in metastatic triple-negative breast cancer
An AI-based digital pathology assessment of PD-L1 identified metastatic triple-negative breast cancer patients with longer progression-free survival on pembrolizumab in ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!