Tag: PD-1

Plasma-derived small extracellular vesicles from head and neck cancer patients suppress T-cell proliferation, trigger apoptosis, and rewire immune checkpoint expression ...

A matching-adjusted indirect comparison of two landmark trials suggests retifanlimab significantly prolongs progression-free survival compared with avelumab in metastatic Merkel ...

A new review details how immune checkpoint inhibitors, cell therapies, vaccines and oncolytic viruses have transformed melanoma treatment while highlighting ...

A new case report describes how the immunotherapy drug pembrolizumab triggered pemphigoid nodularis, a rare blistering skin disease that initially ...

A sweeping review details how immune checkpoint inhibitors, combination regimens, CAR-T cells, vaccines, and oncolytic viruses are transforming treatment of ...

A new review details how microbial imbalances in the gut, airways, mouth, and tumors drive lung cancer progression and undermine ...

A new single-cell study identifies the transcription factor RBPJ and CD103-positive tissue-resident memory T cells as central drivers of successful ...

New research reveals that radiotherapy induces PD-1 expression on tumor-associated monocytes through an adenosine-driven signaling pathway, creating an immunosuppressive cell ...

New research shows that immune checkpoint receptors on human gamma delta T cells are regulated in a lineage- and context-dependent ...

A retrospective real-world study found that neoadjuvant chemoimmunotherapy followed by surgery produced significantly longer overall survival and strong pathologic responses ...