Gut Enzyme LRRK2 Rises in Crohn’s Disease but Not in Parkinson’s or REM Sleep Disorder
A French study finds colonic LRRK2 expression is strongly increased in Crohn's disease but not elevated in Parkinson's disease or ...
Tag: Parkinson’s disease
Fatty Acid Nitroalkenes Show Promise in Taming LRRK2 Hyperactivation in Parkinson’s Disease
New research in npj Parkinson's Disease shows that fatty acid nitroalkenes can inhibit LRRK2 kinase hyperactivation and provide neuroprotection in ...
Parkinson’s Patients on Pills Alone Stay Stuck as Device Therapies Go Unused
The first prospective real-world study of its kind found that most Parkinson's disease patients with uncontrolled motor fluctuations remained on ...
Scientists Clash Over Free Water Imaging as a Marker of Parkinson’s Disease Progression
A published exchange in npj Parkinson's Disease highlights the methodological debate over whether free water imaging can reliably serve as ...
ACE2 Loss May Tie Parkinson’s Disease to Bone Loss Through Shared Brain and Bone Pathways
A new mouse study shows that loss of ACE2 worsens parkinsonian brain pathology while simultaneously disrupting bone-forming and bone-resorbing signaling ...
Free Water Imaging in Parkinson’s Disease Demands Methodological Nuance, Study Argues
Researchers argue that free water imaging in Parkinson's disease produces method-dependent results that resist simple binary interpretation.
Brain Disorders Now Account for More Than a Quarter of Norway’s Disease Burden
A first-of-its-kind analysis of Global Burden of Disease 2023 data finds that brain disorders account for more than a quarter ...
TIMP2 Protein Levels and Gene Variants Trace Ageing and Neurodegeneration in Parkinson’s Disease
New research shows that cerebrospinal fluid TIMP2 levels rise with age and track neurodegeneration in Parkinson's disease, while TIMP2 gene ...
Plant-Derived Nanoparticles Show Promise Against Neurodegenerative Disease
A new review in 3 Biotech details how nanoparticles loaded with herbal compounds like curcumin and resveratrol could overcome the ...
Black Pepper Compound Piperine Emerges as Powerful Potential Parkinson’s Drug in Landmark Study
A new computational study shows that piperine, the pungent alkaloid of black pepper, binds the Parkinson's-related MAO-B enzyme more strongly ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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