Virtual Screening Yields a Potent New MAPKAPK2 Inhibitor Against Pancreatic Cancer
Researchers used structure-based virtual screening of roughly 280,000 compounds to discover compound 77501, a novel and selective MAPKAPK2 inhibitor that ...
Tag: pancreatic cancer
Two Proteins in Tiny Biopsies May Predict Survival in Pancreatic Cancer
A prospective Japanese study finds that combined high expression of PODXL and ITGB1 in preoperative EUS-FNAB biopsy specimens independently identifies ...
PI3K/AKT/mTOR Pathway Emerges as Central Target in Gastrointestinal Cancers
A comprehensive review finds that the PI3K/AKT/mTOR signaling axis drives progression and therapy resistance in gastrointestinal cancers, but clinical success ...
Pancreatic Cancer Scrambles the Body Clock in Breathing and Heart Muscles
New research in mice shows that pancreatic cancer disrupts the circadian clocks of the diaphragm and heart, scrambling daily gene ...
The Mouth’s Microbes May Hold Clues to Cancer’s Origins
A comprehensive new review details how oral microbial dysbiosis, driven by pathogens like Fusobacterium nucleatum and Porphyromonas gingivalis, is increasingly ...
Massive Genetic Study Uncovers 18 DNA Regions Linked to Pancreatic Cancer Risk
A cross-population meta-analysis of over 1.4 million people identified 18 genetic loci for pancreatic cancer, including four new ones, along ...
MRI Signs and Blood Marker Reveal Which Pancreatic Cancer Patients Face Early Recurrence
Researchers in China have built a predictive model combining preoperative MRI features and serum CA19-9 levels that accurately identifies pancreatic ...
AI-Guided Modeling Uncovers Hidden Switches That Could Heat Up Cold Pancreatic Tumors
Researchers at Eindhoven University of Technology combined active learning with mechanistic logic-ODE models to uncover context-specific regulators of the immune-recruiting ...
Shrinking Pancreas on Scans May Signal Earliest Stage of Deadly Cancer
A new review argues that focal atrophy of the pancreas visible on CT scans can signal early pancreatic cancer years ...
Radioactive Microspheres Show Real-World Promise Against Hard-to-Treat Liver Metastases
A large prospective European registry study found that yttrium-90 radioembolization is safe and shows encouraging effectiveness for liver metastases from ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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