Pancreatic Cancers With ATM Defects May Respond to Irinotecan, Study Finds
A new study combining real-world clinical data with CRISPR-edited cell models shows that pancreatic cancers with ATM or CHEK2 mutations ...
Tag: pancreatic cancer
Collagen Scaffold Helps Starved Tumours Switch Fuel and Evade Treatment
University of Sheffield researchers found that type I collagen in tumour scaffolding lets breast and pancreatic cancer cells switch fuel ...
Biweekly Chemo Duo Shows Promise for Pancreatic Cancer Patients Over 75
A prospective Phase II trial in Japan found that biweekly gemcitabine plus nab-paclitaxel produced a 47.1 percent response rate and ...
Engineered fusogenic vaccinia virus arms IL-15 to reprogram tumors and boost antitumor immunity
Researchers engineered a fusogenic oncolytic vaccinia virus that displays IL-15Rα on infected tumor cells to locally trans-present IL-15, reprogramming the ...
Fructose Fuels Pancreatic Cancer: New Vulnerability Found in KRAS G12D Tumors
A new review highlights fructose metabolism as a druggable weakness in KRAS G12D pancreatic tumors and proposes sodium citrate as ...
New Sequencing Method Captures the Neurons Wired into Individual Organs
Researchers have published a two-week protocol called Trace-n-Seq that retrogradely labels neurons innervating a chosen organ and sequences them individually ...
Pan-RAS Inhibitor Daraxonrasib Delivers Landmark Survival Gains in Pancreatic Cancer
Two landmark New England Journal of Medicine studies show the pan-RAS inhibitor daraxonrasib nearly doubles survival in previously treated metastatic ...
Doctors Reach Pancreatic Tumor Through a Vein to Diagnose and Treat It
A case report describes a novel transjugular endovascular biopsy through the portal vein that diagnosed pancreatic cancer after standard biopsies ...
Hormone Pills and Pancreatic Cancer: Massive Analysis Finds Mostly No Link
A new systematic review and meta-analysis of 27 studies finds no consistent link between oral contraceptives, menopausal hormone therapy, or ...
Pancreatic Cancer’s Moving Target: New Framework Calls for Continuously Evolving Treatment
A new review proposes a Dynamic Precision Oncology framework that monitors pancreatic cancer's evolving resistance mechanisms through longitudinal genomic, liquid ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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