Standardized Mouse Dissection Protocols Aim to Fix a Reproducibility Crisis in Neuroscience
Researchers have published five standardized protocols for dissecting mouse brain, spinal cord, cerebrospinal fluid, and sciatic nerve tissue to improve ...
Tag: mouse models
Mouse Models Show Teeth Can Expose Hidden Signs of Rare Bone Disease
New knock-in mouse models of hypophosphatasia show that specific ALPL gene variants shape dental symptoms independently of blood enzyme levels, ...
Immune Fingerprints in Blood Reveal Parkinson’s Disease When Patients Are Sorted First
By stratifying Parkinson's patients into mouse-model-anchored immune subtypes, researchers have built T-cell receptor blood tests that exceed 0.8 AUC, overturning ...
Blocking the Growth Hormone Receptor Extends Mouse Lifespan, Landmark Study Finds
A formal aging study of 351 mice shows for the first time that blocking the growth hormone receptor with an ...
Head-Fixed Mice Learn to Self-Administer Drugs, Opening a New Window on Addiction
A new Nature Protocols article details how to combine head fixation with intravenous drug self-administration in mice, uniting voluntary drug-taking ...
Gut Oxygen Sensor Shields Against Obesity but Adds Nothing to Weight-Loss Surgery
New mouse research shows intestinal HIF1α is unnecessary for the metabolic gains of bariatric surgery but plays a vital protective ...
Scientists Map the Hidden Cellular Matrix Landscapes That Drive Allergic Airway Inflammation
A new imaging mass cytometry pipeline reveals region-specific extracellular matrix environments that shape immune cell behaviour during allergic airway inflammation ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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