Ultrasound Tracks Coronary Dilation in Mouse Model of Kawasaki Disease
High-resolution ultrasound revealed progressive coronary dilation and reduced cardiac function in a mouse model of Kawasaki disease.
Tag: mouse models
Engineered Alpha-Synuclein Mouse Models Reshape Parkinson’s Therapy Testing
A new review details how engineered alpha-synuclein mouse models with defined biochemical defects are transforming Parkinson's disease therapy development.
Estrogen Slows Thoracic Aortic Aneurysm Progression in Marfan Syndrome Mice
In a severe mouse model of Marfan syndrome, estrogen treatment and endogenous ovarian hormones slowed ascending thoracic aortic aneurysm dilation ...
Beta-Alanine Partially Mitigates Symptoms of Glucocorticoid Excess in Mice
In a study of female mice, beta-alanine supplementation partially attenuated symptoms of glucocorticoid excess and preserved glucose tolerance.
New Protocol Reliably Induces Advanced Liver Cancer in Male and Female Mice
A sequential regimen combining chemical carcinogens and a Western diet reliably produces advanced hepatocellular carcinoma in male and female mice ...
Refined Tissue Chemistry Lets Mass Spectrometry Maps Reveal Tumor Metabolism
An optimized on-tissue derivatization workflow using 4-APEBA and EDC enables confident MALDI-MSI mapping of carbonyl- and carboxyl-containing metabolites in mouse ...
Topological Signatures and Visual Words Give Computers a Sharper Eye for Diseased Muscle
A new computational framework called TopoBoW combines topological data analysis with visual word encoding to distinguish healthy from pathological mouse ...
Gene Screens in Aged Mice Reveal Two Distinct Routes to Restore Tumor-Fighting T Cells
Genetic screens in aged mice identify Dusp5 and Zfp219 as regulators whose deletion can restore anti-tumor T cell function, with ...
CMPK2–mtDNA Axis Drives Doxorubicin Heart Damage, Study Finds
A mouse study identifies the mitochondrial enzyme CMPK2 as a key mediator of doxorubicin heart injury and reports that flavin ...
Tumour suppressor gene loss sparks childhood brain tumour in mice, revealing hidden driver
New mouse experiments show that losing the tumour suppressor Apc in pituitary stem cells is enough to cause adamantinomatous craniopharyngioma ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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