Tag: mouse models

A mouse study found that adipocyte-derived PDGF-D protects against age-related obesity by maintaining lymphatic function and endothelial cell integrity.

Elevated hippocampal 2-AG and reduced prefrontal neurotransmitter levels accompanied behavioral recovery after short-term fluoxetine treatment in stressed male mice.

Researchers found that gut antibody IgA works with epithelial receptor DMBT1 to temper cell proliferation and curb colorectal cancer susceptibility ...

An engineered biomimetic nanoplatform reversed sleep deprivation-induced cognitive deficits and neuroinflammation in mice by restoring homeostatic microglial phenotypes.

Researchers developed domain-alteration chimeras that bind two cooperating proteins to suppress prostate cancer tumors in preclinical models while sparing normal ...

A study in mice shows that the rare APOE Christchurch mutation prevents the accumulation of toxic proteins tied to Parkinson's ...

Researchers identify Maternal Embryonic Leucine Zipper Kinase as a key driver of vascular smooth muscle cell phenotypic transition in neointimal ...

Esketamine improved cognitive performance and suppressed neuronal apoptosis in perioperative neurocognitive disorder models by stabilizing DHCR24 expression through METTL3-mediated m6A ...

Researchers found that eukaryotic translation initiation factor 3 subunit I promotes gastric cancer progression by stabilizing YAP and driving intracellular ...

Research in mouse models demonstrates that cerebellar alpha-synuclein pathology independently causes gait and balance deficits characteristic of Parkinsonian postural instability.