Tag: mouse models

A mouse study found that removing ANKRD11 enhanced CD8+ T-cell activity against chronic hepatitis B virus infection and cancer, but ...

A mouse study found that chronic stress shortened primary cilia on amygdala astrocytes, while restoring the structures improved some stress-related ...

In mouse cerebellar slice cultures, blocking mGluR1 partially restored dendritic, spine and postsynaptic abnormalities in Purkinje cells carrying the SCA14-associated ...

Mouse infection experiments show that Mycobacterium tuberculosis remains difficult for innate immunity to clear across ultra-low-dose, microbiota-primed, and Legionella-primed models.

Researchers report that mouse and human beige adipocytes can increase energy expenditure through a futile sodium and potassium transport cycle ...

A mouse study found that organized immune hubs in skull bone marrow respond to nervous-system antigens and influence tumor immunity ...

A mouse study found that directly reducing lung cancer cells’ dependence on phospholipase D1 significantly slowed tumor growth, but clinical ...

An experimental study in ALS models found that an interferon-beta signal can increase motor-neuron immunoproteasome activity and clear aggregation-prone TDP-43 ...

SGK1 inhibition reduced fibrosis and airway obstruction in a mouse bronchiolitis obliterans model and suppressed fibrosis-related molecular changes in human ...

Human postmortem tissue, cultured cells and mouse experiments implicated abnormal ABCA1-dependent cholesterol trafficking in Parkinson’s-related neurodegeneration.