Tag: mouse models

Researchers developed domain-alteration chimeras that bind two cooperating proteins to suppress prostate cancer tumors in preclinical models while sparing normal ...

A study in mice shows that the rare APOE Christchurch mutation prevents the accumulation of toxic proteins tied to Parkinson's ...

Researchers identify Maternal Embryonic Leucine Zipper Kinase as a key driver of vascular smooth muscle cell phenotypic transition in neointimal ...

Esketamine improved cognitive performance and suppressed neuronal apoptosis in perioperative neurocognitive disorder models by stabilizing DHCR24 expression through METTL3-mediated m6A ...

Researchers found that eukaryotic translation initiation factor 3 subunit I promotes gastric cancer progression by stabilizing YAP and driving intracellular ...

Research in mouse models demonstrates that cerebellar alpha-synuclein pathology independently causes gait and balance deficits characteristic of Parkinsonian postural instability.

A study in mice reveals that deleting Stat3 in activated astrocytes dampens specific inflammatory transcripts without altering prion disease progression ...

Researchers developed a machine learning neural network named CORAL that identified coronary microvascular disease in mice using Doppler echocardiographic coronary ...

In mouse and chondrocyte models, KAT7 was shown to drive osteoarthritis cartilage degeneration by epigenetically activating Nlrp3 transcription via H3K14 ...

High-resolution ultrasound revealed progressive coronary dilation and reduced cardiac function in a mouse model of Kawasaki disease.