Gene Therapy Now Leads Spinal Muscular Atrophy Treatment as Real-World Sequencing Patterns Emerge
A large US claims analysis shows that after widespread newborn screening, gene replacement therapy has become the dominant first treatment ...
Tag: motor neuron disease
Blood Tau Rises in ALS but Tracks Motor Neuron Damage, Not Thinking Skills
A large multicenter study finds that plasma p-tau181, an approved Alzheimer's blood biomarker, is elevated in ALS and rises over ...
Muscle Mass and Sarcopenia Emerge as Powerful Predictors of Survival in ALS
A Spanish cohort study finds that low appendicular skeletal muscle mass and sarcopenia independently predict mortality in ALS, with sarcopenia ...
Base Editing Corrects Gene Mutation and Slows Motor Neuron Disease in Mice
Kyoto University researchers used adenine base editing to correct the TFG mutation behind HMSN-P, delaying disease onset and extending survival ...
ALS Protein Clumps Found Far Beyond the Brain Suggest a Whole-Body Disease
A new review finds that the pathological protein TDP-43, the hallmark of ALS, accumulates in muscle, skin, glands and other ...
Human ALS Seeds Transmit Two Distinct SOD1 Aggregation Strains in Mice
Seeds prepared from the spinal cords of ALS patients homozygous for the SOD1 D90A mutation transmitted two distinct strains of ...
Motor Neuron Disease Deaths Rise in the US, but Age-Adjusted Rates Hold Steady
A 26-year CDC WONDER analysis of 170,570 US deaths finds motor neuron disease death counts rose 47 percent while age-adjusted ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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