Alcoholism Drug Disulfiram Restores Fluconazole Power Against Resistant Candida
Egyptian researchers found that the alcohol-aversion drug disulfiram synergizes with fluconazole, downregulates the Cdr1 efflux pump, and inhibits biofilm formation ...
Tag: molecular docking
Azo Compound Shows Promise Against Chagas and Leishmania Parasites
A synthetic azobenzenoid compound called CaCS2 shows broad-spectrum activity against Leishmania amazonensis and Trypanosoma cruzi with low human cell toxicity, ...
Brown Seaweed From Moroccan Coast Shows Striking Antidiabetic Power in Lab Tests
A new study reports the first comprehensive in vitro and in silico evaluation of the brown alga Cladostephus spongiosus, revealing ...
Copper Supercharges Beta-Carboline Metal Complexes Against Aggressive Breast Cancer
New nickel and copper metallocarboxylate complexes of a tryptophan-derived beta-carboline alkaloid bind DNA in the minor groove and show dramatic, ...
Black Pepper Compound Piperine Emerges as Powerful Potential Parkinson’s Drug in Landmark Study
A new computational study shows that piperine, the pungent alkaloid of black pepper, binds the Parkinson's-related MAO-B enzyme more strongly ...
Salt-Tolerant Coastal Plants Reveal Potent Antioxidant and Anti-Inflammatory Compounds
A new study finds that two salt marsh plants from India's Cuddalore coast, Suaeda maritima and Sesuvium portulacastrum, are rich ...
Moth Olfactory Receptor Keeps the Same Chemical Codes Across Two Crop Pests
A new comparative study shows that the ionotropic receptor IR75q.2 in two Spodoptera moth pests shares conserved ligand tuning, binding ...
Microwave Method Turns Shrimp Shell Waste Into Wound-Healing Chitosan
A microwave-assisted extraction method produces higher-yield, higher-quality chitosan from shrimp shell waste with up to 94.6 percent less energy than ...
Tilfrinib Blocks PTK6 to Curb Ovarian Cancer Cell Growth and Spread
A new study shows that inhibiting the kinase PTK6 with the drug tilfrinib suppresses the proliferation and migration of ovarian ...
Virtual Screening Uncovers Promising Non-Covalent Inhibitors of Human Rhinovirus 3C Protease
A computational screening study has identified two non-covalent inhibitor candidates against the human rhinovirus 3C protease that outperform the reference ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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