Exercise fails to restore mitochondrial function in high-phosphate-fed male mice
In male mice, voluntary exercise improved treadmill endurance and changed muscle gene expression but did not reverse high-phosphate-diet-related impairment of ...
Tag: mitochondrial respiration
Small spatial-transcriptomics study links metabolism to T-cell exclusion in esophageal adenocarcinoma
A small clinical study linked lipid metabolism and mitochondrial respiration to low CD8-positive T-cell infiltration in esophageal adenocarcinoma using spatial ...
NDUFS1 links mitochondrial respiration to aggressive breast cancer behavior
A preclinical study links elevated NDUFS1, a mitochondrial complex I subunit, to breast cancer progression through increased respiration and PROX1–c-Myc ...
Surplus Bypass Graft Segments Reveal Real-Time Mitochondrial Respiration in Intact Human Arteries
Researchers at the Medical University of Gdańsk have for the first time measured real-time mitochondrial respiration in intact human artery ...
Hidden Immune Overdrive in Blood Reveals Parkinson’s Patients Carrying Alzheimer’s Co-Pathology
A multidimensional immunological study of early-stage Parkinson’s disease uncovers a hyperinflammatory, hypermetabolic blood signature that separates patients with Alzheimer’s co-pathology ...
Smoke Tree Flavonoids Rewrite Gene Activity in Leukemia Cells, Study Finds
A transcriptomic study shows that three flavonoids from smoke tree heartwood suppress leukemia cell growth by shutting down RNA processing ...
Lingonberry Extract Starves Oral Cancer Cells by Rewiring Their Energy Metabolism
A cold-pressed lingonberry extract selectively inhibited the proliferation and invasion of oral cancer cells in laboratory experiments by disrupting the ...
Hydrogen Sulfide Helps Plants Survive Drought by Reshaping a Key Metabolic Enzyme
New research shows that hydrogen sulfide boosts drought tolerance in Arabidopsis by simultaneously reshaping the splicing and persulfidation of the ...
Cancer Cells Rewire Their Fuel Supply When This Growth Signal Switches On
New research reveals that HGF/c-MET signaling reprograms glutamine metabolism in MET-amplified head and neck cancer cells through ERK-dependent induction of ...
Hidden Microproteins in the Human Brain Map a New Frontier of Alzheimer’s Disease
A new atlas catalogues 1,067 unannotated microproteins in the human frontal cortex and reveals that a subset, including an MKKS-derived ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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