Tag: microglia

A literature review links age-related DNA leakage and persistent cGAS–STING signaling to chronic brain inflammation across several neurological disorders.

A Nature Neuroscience study in mouse and cell models reports that losing the Parkinson's risk protein NgBR in microglia triggers ...

A Nature Neuroscience study in mouse models and human multiple sclerosis tissue identifies a pro-inflammatory microglial state marked by lysosomal ...

A new theoretical framework proposes that early adversity alters the developing biological architecture through which later inputs are transformed into ...

A conceptual review proposes that disrupted circadian timing may reinforce neuroinflammation, impair glymphatic clearance and alter molecular clock activity.

Microglia, the brain's resident immune cells, deploy cytokines, chemokines, complement proteins, and phosphatidylserine recognition systems to build and refine neural ...

A new narrative review maps how vitamin D deficiency may sit at the mechanistic crossroads of neuropathic pain and cognitive ...

In BV2 microglial cells, esketamine suppressed lipopolysaccharide-induced M1 polarization by selectively acting on the NMDAR2A receptor subtype and activating mTOR ...

A new nanomaterial called TPTN reduces uveitis inflammation by suppressing microglial activation and inhibiting the JAK2-STAT1 signaling pathway in mouse ...

A new review argues that inflammatory signaling between microglia and astrocytes may help initiate and maintain the central sensitization underlying ...