Tag: METTL3

A new review in Molecular Cancer maps the bidirectional crosstalk between deubiquitinases and m6A RNA modification, revealing a coupled regulatory ...

Researchers at Nanjing Medical University report that the m6A-stabilized circular RNA circLPAR3 suppresses ferroptosis through the PCBP2/CHAC1 axis, driving docetaxel ...

New research shows that the Super Elongation Complex drives both stem cell reprogramming and neural differentiation by releasing paused RNA ...

A new study reveals how lactate-driven lactylation of histone and non-histone proteins in liver cancer activates a METTL3-FDFT1 cholesterol pathway ...

New research shows that the m6A-writing enzyme METTL3 speeds recovery from bacterial liver abscesses by methylating Nrf2 mRNA, which arms ...

A new study reveals how hypoxia-driven ER-mitochondria contact sites and the membrane-rupturing protein NINJ1 conspire to destroy the gastric lining ...

Researchers have identified a METTL3/IGF2BP1-USP16-FUBP1-LDHA regulatory axis that drives glycolysis-dependent progression and gemcitabine resistance in pancreatic ductal adenocarcinoma, highlighting USP16 ...

A new study shows that the RNA-modifying enzyme METTL3 and its m6A marks are essential for the postnatal specification of ...

A sweeping review reveals how the RNA modification N6-methyladenosine orchestrates lung cancer progression, drug resistance, immunotherapy response, and survival prediction.

A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...